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TranscriptomicsIGR_PhilippeVielh_THY_CGH
Although fine needle aspiration (FNA) cytology is helpful in determining whether thyroid nodules are benign or malignant, this distinction remains challenging in follicular neoplasms. Identification of genomic alterations in cytological specimens that distinguish between benign and malignant follicu...
ORGANISM(S): Homo sapiens 
2013-07-01 | E-MTAB-1575 | biostudies-arrayexpress
TranscriptomicsIGR_IsabellePLO_MPN_IPS
Genomic profiling of progenitor CD34+ cells and their respective induced pluripotent stem cells from MPN patients
ORGANISM(S): Homo sapiens 
2014-02-08 | E-MTAB-1494 | biostudies-arrayexpress
TranscriptomicsEfficacy of trametinib and dabrafenib associated with radioactive iodine for the treatment of refractory metastatic differentiated thyroid cancer (KRAS cohort)
Efficacy of a selective MEK (trametinib) and BRAFV600E (dabrafenib) inhibitors associated with radioactive iodine (RAI) for the treatment of refractory metastatic differentiated thyroid cancer with RAS (current cohort) or BRAFV600E mutation. To evaluate the objective response rate according to RECIS...
ORGANISM(S): Homo sapiens 
2023-09-01 | E-MTAB-12900 | biostudies-arrayexpress
TranscriptomicsEfficacy of trametinib and dabrafenib associated with radioactive iodine for the treatment of refractory metastatic differentiated thyroid cancer
Efficacy of a selective MEK (trametinib) and BRAFV600E (dabrafenib) inhibitors associated with radioactive iodine (RAI) for the treatment of refractory metastatic differentiated thyroid cancer with RAS or BRAFV600E mutation. To evaluate the objective response rate according to RECIST criteria in thy...
ORGANISM(S): Homo sapiens 
2023-09-01 | E-MTAB-12837 | biostudies-arrayexpress
TranscriptomicsThe protein phosphatase 2A regulatory subunit PR70 is a gonosomal melanoma tumor suppressor gene
Men with melanoma have a significantly worse prognosis than women, and the biological underpinnings of this difference are unknown. The current study demonstrates that loss of the inactivated X chromosome in melanomas arising in females is strongly associated with poor distant metastasis free surviv...
ORGANISM(S): Homo sapiens 
2016-08-01 | E-GEOD-66839 | biostudies-arrayexpress
TranscriptomicsGene profiling of human primary fibroblasts treated with IDH2 inhibitor
Gene profiling of human primary fibroblasts treated with IDH2 inhibitor or vehicle (DMSO), for 3 or 6 days
ORGANISM(S): Homo sapiens 
2023-03-22 | E-MTAB-12637 | biostudies-arrayexpress
TranscriptomicsCGH analysis of human colorectal carcinoma HCT116 cells that escaped from entescence
The engulfment of live cells by other live cells, also known as cannibalism, can result in the death of engulfed cells. Recently, we show that autophagy favors the accumulation of E-cadherins on the surface of cannibal cells, thereby enhancing their capacity to engulf and eliminate live cells. Impor...
ORGANISM(S): Homo sapiens 
2019-01-01 | E-MTAB-6802 | biostudies-arrayexpress
TranscriptomicsCIT - Homo sapiens - APUP - Genomic aberrations in Lung Adenocarcinoma in Never Smokers
41 lung adenocarcinoma from never-smokers hybridized on Illumina SNP arrays on 13 HumanCNV370-Quadv3 chips. High-resolution array comparative genomic hybridization analysis of lung adenocarcinoma in 41 never smokers for identification of new minimal common regions (MCR) of gain or loss. The SNP arr...
ORGANISM(S): Homo sapiens 
2011-07-28 | E-TABM-1169 | biostudies-arrayexpress
TranscriptomicsIGR_CREMEC_CGH_STYDY_LL
Patient-derived xenograft models are considered to represent the heterogeneity of human cancers and might be more relevant preclinical models to evaluate effective therapeutic agents. Our consortium joins efforts to extensively develop and characterize a new collection of patient-derived colorectal ...
ORGANISM(S): Homo sapiens 
2012-07-27 | E-MTAB-992 | biostudies-arrayexpress
TranscriptomicsIGR_CREMEC_GEX_STUDY_LL
Patient-derived xenograft models are considered to represent the heterogeneity of human cancers and might be more relevant preclinical models to evaluate effective therapeutic agents. Our consortium joins efforts to extensively develop and characterize a new collection of patient-derived colorectal ...
ORGANISM(S): Homo sapiens 
2012-07-27 | E-MTAB-991 | biostudies-arrayexpress
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