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The blood-brain barrier (BBB) consists of specific physical barriers, enzymes and transporters, which together maintain the necessary extracellular environment of the central nervous system (CNS). The main physical barrier is found in the CNS endothelial cell, and depends on continuous complexes of ...
ORGANISM(S): Mus musculus 
To characterize the vascular proteome of the brain, proteins were extracted from the brain microvascular fragments isolated from adult mice using CD31-coated magnetic beads. The proteins were enzymatically digested and subjected to mass spectrometric analysis
ORGANISM(S): Mus Musculus (mouse) 
Vascular smooth muscle cells (VSMC) are important for contraction, blood flow distribution and regulation of blood vessel diameter, but to what extent they contribute to the integrity of blood vessels and blood-brain barrier function is less well understood. In this report, we explored the impact of...
ORGANISM(S): Mus musculus 
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