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TranscriptomicsRNAseq of iPSC derived cardiomyocytes in response to endothelin-1 as a model for cardiac hypertrophy
The study aims to develop an in vitro model of cardiac hypertrophy using human induced pluripotent stem cells (hPSCs). Human stem cell based disease models are important for reducing the number of animals used in research and to get data the is more relevant to humans. We stimulated hiPSCs derived c...
ORGANISM(S): Homo sapiens 
2020-09-01 | E-MTAB-8548 | biostudies-arrayexpress
TranscriptomicsHigh-resolution genomic profiling of male breast cancer reveals differences hidden behind the similarities with female breast cancer.
Male breast cancer (MBC) is extremely rare and poorly characterized on the molecular level. Using high-resolution genomic data, we aimed to characterize MBC by genomic imbalances and to compare it with female breast cancer (FBC), and further to investigate whether the genomic profiles hold any progn...
ORGANISM(S): Homo sapiens 
2016-07-03 | E-GEOD-50512 | biostudies-arrayexpress
TranscriptomicsscRNA-seq data for Distinct Stem Cell Identities Converge into Shared Erythroid Stress in ERCC6L2 Disease and Shwachman-Diamond Syndrome
This study includes single-cell RNA sequencing of human samples across ERCC6L2 disease (ED), Shwachman-Diamond syndrome (SDS), acute myeloid leukemia (AML), and healthy controls. ED, SDS, and AML samples were processed for single-cell capture, followed by library preparation and sequencing. Sequenci...
ORGANISM(S): Homo sapiens 
2026-06-03 | E-MTAB-16984 | biostudies-arrayexpress
UnknownAssociation Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study.
Not available
S-EPMC5638008 | biostudies-literature
UnknownIdentification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.
Not available
S-EPMC3696959 | biostudies-literature
UnknownAnalysis of shared heritability in common disorders of the brain.
Not available
S-EPMC6097237 | biostudies-literature
UnknownUpdate on the third international stroke trial (IST-3) of thrombolysis for acute ischaemic stroke and baseline features of the 3035 patients recruited.
Not available
S-EPMC3286387 | biostudies-literature
UnknownGenetic Risk Score for Intracranial Aneurysms: Prediction of Subarachnoid Hemorrhage and Role in Clinical Heterogeneity.
Not available
S-EPMC9951795 | biostudies-literature
UnknownThe benefits and harms of intravenous thrombolysis with recombinant tissue plasminogen activator within 6 h of acute ischaemic stroke (the third international stroke trial [IST-3]): a randomised controlled trial.
Not available
S-EPMC3386495 | biostudies-literature
UnknownEffect of alteplase on the CT hyperdense artery sign and outcome after ischemic stroke.
Not available
S-EPMC4731690 | biostudies-literature
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