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TranscriptomicsDefining precision probes which differentiate between the activity of type I and type II interferons.
To define probes which differentiate between the activity of type I or type II IFN, a human submandibular gland (HSG) cell line was cultured for 48 hours in the absence or presence of IFNa or IFNg. Gene expression was assayed at 4, 12, 24 or 48 hours and was compared to gene expression in untreated ...
ORGANISM(S): Homo sapiens 
2012-10-08 | E-GEOD-41291 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Cockayne Syndrome human fibroblasts lacking functional CSB, a SWI/SNF-like ATPase, to determine the molecular defect in CS
Cockayne syndrome (CS) is an inherited neurodevelopmental disorder with progeroid features. Although the genes responsible for CS have been implicated in a variety of DNA repair- and transcription-related pathways, the nature of the molecular defect in CS remains mysterious. We sought to define this...
ORGANISM(S): Homo sapiens 
2007-07-03 | E-GEOD-3407 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of retinal tumor onset and progression in a zebrafish optic pathway tumor line
Heterozygous adults of the zebrafish transgenic line Tg(flk1:RFP)is18 develop tumors in the retina, optic nerve and optic tract. Transcriptome profiling of dissected retina or retinal tumor tissue from age matched 6 month old sibling wild type and Tg(flk1:RFP)is18/+ fish was generated by 100 bp pair...
ORGANISM(S): Danio rerio 
2014-12-10 | E-MTAB-2886 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human neuroblastoma cell line SHEP expressing a MYNC trasngene against controls which have the transgene silenced by tetracycline
MYCN is an oncogene amplified in approximately 20% of all neuroblastomas and 50% of high risk neuroblastoma. It is a transcription factor regulating the expression of genes involved in proliferation and apoptosis.We would like to identify genes potentially regulated by MYCN in a conditional MYCN exp...
ORGANISM(S): Homo sapiens 
2010-02-18 | E-MEXP-2340 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Arabidopsis auxin resistant axr4 mutant and wild-type Col0
The plant hormone auxin represents an important regulator of growth and development. Significant insight into the mechanisms of auxin action have been obtained from studies of auxin resistant mutants such as aux1 and axr3. The Arabidopsis axr4 mutant was identified in a screen for auxin resistant ro...
ORGANISM(S): Arabidopsis thaliana 
2008-06-14 | E-GEOD-6168 | biostudies-arrayexpress
UnknownCross-attention enables deep learning on limited omics-imaging-clinical data of 130 lung cancer patients.
Not available
S-EPMC11294841 | biostudies-literature
Unknown#COVIDisAirborne: AI-Enabled Multiscale Computational Microscopy of Delta SARS-CoV-2 in a Respiratory Aerosol.
Not available
S-EPMC8609898 | biostudies-literature
UnknownSevere intraocular lens tilt after the Yamane technique.
Not available
S-EPMC11757069 | biostudies-literature
TranscriptomicsTranscription profiling of hippocampus of CV mice (C57Bl x VM/Dk) inoculated with ME7 scrapie to determine the molecular events that accompany the scrapie-associated hippocampal neuropathology
A study of differential gene expression in the hippocampus of CV mice (C57Bl x VM/Dk) inoculated with ME7 scrapie to determine the molecular events that accompany the scrapie-associated hippocampal neuropathology. Analysis was performed at 170 days post infection, a timepoint that coincides with se...
ORGANISM(S): Mus musculus 
2005-05-01 | E-MEXP-284 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of benign epithelial and prostate cancer cell lines derived from the same patient
Copy number alterations in a matched pair of benign epithelial and prostate cancer cell lines derived from the same patient were assessed using array-based comparative genomic hybridisation (aCGH). the cancer cell line showed a gain of chromosome 7, deletion of chromosome 8, gains and losses in chro...
ORGANISM(S): Homo sapiens 
2006-08-04 | E-MEXP-803 | biostudies-arrayexpress
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