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TranscriptomicsAltered gene expression in Werner & Bloom syndromes is associated with sequences having G-quadruplex forming potential
The human Werner and Bloom syndromes (WS and BS) are caused by deficiencies in the WRN and BLM RecQ helicases, respectively. WRN, BLM and their S. cerevisiae homologue Sgs1, are particularly active in vitro in unwinding G-quadruplex DNA (G4-DNA), a family of non-canonical nucleic acid structures fo...
ORGANISM(S): Homo sapiens 
2009-12-09 | E-GEOD-19205 | biostudies-arrayexpress
TranscriptomicsGene expression signature reflects differentiation differences rather than telomere maintenance mechanism
A gene expression signature purporting to distinguish between telomerase and ALT immortalization has recently been described (Lafferty-Whyte et al., 2009). This was obtained as the intersection of two independent signatures, one obtained from cell lines and the other from a panel of liposarcomas, w...
ORGANISM(S): Homo sapiens 
2010-03-06 | E-GEOD-20559 | biostudies-arrayexpress
UnknownRisk of COVID-19 after natural infection or vaccination.
Not available
S-EPMC10518569 | biostudies-literature
UnknownGlucose metabolism patterns: A potential index to characterize brain ageing and predict high conversion risk into cognitive impairment.
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S-EPMC9616982 | biostudies-literature
UnknownCirculating natriuretic peptide concentrations reflect changes in insulin sensitivity over time in the Diabetes Prevention Program.
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S-EPMC4158711 | biostudies-literature
UnknownConfirming glycemic status in the Diabetes Prevention Program: implications for diagnosing diabetes in high risk adults.
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S-EPMC3594066 | biostudies-literature
UnknownEffects of genetic variants previously associated with fasting glucose and insulin in the Diabetes Prevention Program.
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S-EPMC3439414 | biostudies-literature
UnknownDiabetes autoantibodies do not predict progression to diabetes in adults: the Diabetes Prevention Program.
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S-EPMC4138247 | biostudies-literature
UnknownExtension of type 2 diabetes genome-wide association scan results in the diabetes prevention program.
Not available
S-EPMC2518503 | biostudies-literature
UnknownShort and long-term lifestyle coaching approaches used to address diverse participant barriers to weight loss and physical activity adherence.
Not available
S-EPMC4015875 | biostudies-literature
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