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High-intensity physical activity has major impacts in different parts of the body. However, the regulatory coordination between different tissues to support the high physical demands is poorly understood. Here we performed a multi-omics analysis of blood plasma, urine and saliva from a group of fire...
2025-07-03 | MTBLS1891 | MetaboLights
Viruses are obligate intracellular parasites that exploit the host metabolic machineries to meet their extraordinary biosynthetic demands. Integrative transcriptomic and lipidomic profiling confirmed that Middle East respiratory syndrome coronavirus (MERS-CoV) infection reprograms the host lipid met...
2018-11-26 | MTBLS762 | MetaboLights
Host cell lipids play a pivotal role in the pathogenesis of respiratory virus infection. However, a direct comparison of the lipidomic profile of influenza virus and rhinovirus infections is lacking. In this study, we first compared the lipid profile of influenza virus and rhinovirus infection in a ...
2022-11-15 | MTBLS2352 | MetaboLights
This study assesses fatty acid composition of lipids in matched maternal plasma and placental tissue from lean, obese and gestational diabetes (GDM) women stratified by fetal sex. Obesity and GDM are associated with adverse pregnancy outcomes and program the offspring for cardiometabolic disease in ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-06-09 | MSV000094962 | GNPS
To characterise the transcriptional response in brain of Sockeye Salmon (Oncorhynchus nerka) that were persistently infected with infectious hematopoietic necrosis virus (IHNV) and to determine whether carrying the IHNV affects the ability to respond to other immunological challenges we compared the...
ORGANISM(S): Oncorhynchus nerka 

Exercise enhances physical performance and reduces the risk of many disorders such as cardiovascular disease, type 2 diabetes, dementia and cancer. Exercise characteristically incites an inflammatory response, notably in skeletal muscles. While some effector mechanisms have been identified, regul...

2023-10-10 | MTBLS8391 | MetaboLights
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