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MetabolomicsMetabolic Profiling of Escherichia coli-Based Cell-Free Expression Systems for Process Optimization
Biotechnology has transformed the production of various chemicals and pharmaceuticals due to its efficient and selective processes, but it is inherently limited by its use of live cells as 'biocatalysts.' Cell-free expression (CFE) systems, which use a protein lysate isolated from whole cells, have ...
2020-06-02 | MTBLS1079 | MetaboLights
ProteomicsRe-examining the role of Cdc14 phosphatase in mitotic exit
Given that Cdc14 enzymes are so highly conserved, we questioned whether budding yeast Cdc14 could really have such a different influence on Cdk site dephosphorylation. We used quantitative phosphoproteomics to directly measure the in vivo specificity of budding yeast Cdc14 and found that it very sel...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2017-07-13 | PXD005237 | Pride
Protein phosphatase Mitosis Cdc14 Cdk Mitotic exit Phosphoproteomics Cyclin-dependent kinase 
UnknownRich club analysis in the Alzheimer's disease connectome reveals a relatively undisturbed structural core network.
Not available
S-EPMC4504816 | biostudies-literature
UnknownMultiplexed Assays of Variant Effect and Automated Patch Clamping Improve <i>KCNH2</i>-LQTS Variant Classification and Cardiac Event Risk Stratification.
Not available
S-EPMC11611689 | biostudies-literature
UnknownGenome-wide association analysis of hippocampal volume identifies enrichment of neurogenesis-related pathways.
Not available
S-EPMC6787090 | biostudies-literature
UnknownEvaluation of a national digital pre-implantation biopsy service for deceased-donor kidney transplantation in the UK (Pithia trial); a stepped-wedge cluster randomised registry trial.
Not available
S-EPMC12304751 | biostudies-literature
GenomicsNational Human Genome Research Institute Tumor Sequencing Project (TSP) - Lung Adenocarcinoma

The Tumor Sequencing Project (TSP) Consortium is a collaboration among participants at the Baylor College of Medicine Human Genome Sequencing Center, the Broad Institute Genome Sequencing Platform, the Dana Farber Cancer Institute, the Memorial Sloan-Kettering Cancer Center, the Genome Seque...

phs000144.v1.p1 | EGA
UnknownA recurrent 16p12.1 microdeletion supports a two-hit model for severe developmental delay.
Not available
S-EPMC2847896 | biostudies-literature
GenomicsGenome wide association study for Bladder Cancer Risk

This study funded by the National Cancer Institute (NCI) involves conducting a genome-wide association study of common genetic variants to identify markers of susceptibility to bladder cancer.

This bladder GWAS has led to the discovery of three novel regions in the genome associated with...

phs000346.v1.p1 | EGA
UnknownEfficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine.
Not available
S-EPMC7787219 | biostudies-literature
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