Johnson T M TM - OmicsDI

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Unknown (804)
Genomics (8)
Transcriptomics (7)
Proteomics (6)
Metabolomics (6)

Organisms

Homo sapiens (15)
Oncorhynchus nerka (1)
Fragilariopsis cylindrus (1)
Arabidopsis thaliana (1)
Mus musculus (1)

Repository

biostudies-arrayexpress (8)
EGA (7)
MetaboLights (6)
pride (5)
MassIVE (1)

Tissue

Cell culture (2)
Breast epithelium (1)
Colon (1)
Hepatocyte (1)
Liver (1)
T cell (1)

Disease

Brain cancer (1)
Breast cancer (1)
Colon cancer (1)
Type 2 diabetes mellitus (1)

Technology Type

Mass Spectrometry (5)
NMR spectroscopy (4)
Bottom-up proteomics (3)
Mass spectrometry (2)
Data-independent acquisition (2)
Illumina HumanExome-12v1_A-GenCall, zCall, GenoSNP, - Illuminus (1)
Data-dependent acquisition (1)
Shotgun proteomics (1)

Instrument Platform

Nuclear Magnetic Resonance (NMR) - (3)
LTQ Orbitrap (1)
Bruker (1)
Liquid Chromatography MS - Positive (LC-MS (Positive)) (1)
Liquid Chromatography MS - negative - reverse phase (1)
Liquid Chromatography MS - positive - reverse phase (1)

Publication Date

2021 (3)
2014 (2)
2011 (2)
2010 (2)
2024 (2)
2025 (2)
2008 (1)
2006 (1)
2016 (1)
2022 (1)
2017 (1)
2026 (1)
2019 (1)

CHEBI ID

CHEBI:15428 (3)
CHEBI:16449 (3)
CHEBI:17234 (3)
CHEBI:25017 (3)
CHEBI:27266 (3)
CHEBI:15347 (2)
CHEBI:15366 (2)
CHEBI:15724 (2)
CHEBI:15741 (2)
CHEBI:15891 (2)
CHEBI:16737 (2)
CHEBI:16811 (2)
CHEBI:16919 (2)
CHEBI:18186 (2)
CHEBI:24898 (2)
CHEBI:25094 (2)
CHEBI:26986 (2)
CHEBI:30751 (2)
CHEBI:30769 (2)
CHEBI:30794 (2)
CHEBI:46195 (2)
CHEBI:78320 (2)
CHEBI:10049 (1)
CHEBI:10093 (1)
CHEBI:101085 (1)
CHEBI:10642 (1)
CHEBI:109895 (1)
CHEBI:1109 (1)
CHEBI:12387 (1)
CHEBI:124991 (1)

Metabolite Name

Creatine (2)
Glycine (2)
Leucine (2)
Lysine (2)
Tyrosine (2)
(1'S,2R,2'R,10'S,11'S,15'S)-17'-hydroxy-2',15'-dimethylspiro[oxolane-2,14'-tetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadecane]-6',8'-diene-5,5'-dione (1)
(1-{1-[(4-hydroxy-3-methoxyphenyl)methyl]-7,8-dimethoxy-2,2-dimethyl-1,2,3,4-tetrahydro-2λ⁵-isoquinolin-2-yl}ethylidene)-λ⁴-oxidanyliumyl (1)
(10,14a-dihydroxy-2,2,4a,6a,6b,9,9,12a-octamethyl-docosahydropicen-13-yl)oxidanesulfonic acid (1)
(10S,14S)-10,14,20-trimethyl-16-methylidene-22-azahexacyclo[12.10.0.0²,¹¹.0⁵,¹⁰.0¹⁵,²³.0¹⁷,²²]tetracosan-5-ylium-7-olate (1)
(12aR)-4-(dimethylamino)-4a,5,10,12a-tetrahydroxy-6-methylidene-1,2,3,4,4a,5,5a,6,11,11a,12,12a-dodecahydrotetracene-1,3,11,12-tetrone (1)
(12aR)-7-chloro-4-(dimethylamino)-4,6,10,12a-tetrahydroxy-1,2,3,4,4a,5,5a,6,11,11a,12,12a-dodecahydrotetracene-1,3,11,12-tetrone (1)
(12aS)-4,7-bis(dimethylamino)-10,12,12a-trihydroxy-1,3,11-trioxo-9-(2-oxoacetamido)-1,2,3,4,4a,5,5a,6,11,11a,12,12a-dodecahydrotetracene-2-carboximidic acid (1)
(12aS)-9-{[2-(tert-butylamino)-1-hydroxyethylidene]amino}-4,7-bis(dimethylamino)-5,10,12,12a-tetrahydroxy-1,3,11-trioxo-1,2,3,4,4a,5,5a,6,11,12a-decahydrotetracene-2-carboximidic acid (1)
(13-{[5-(acetyloxy)-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-1,6,6,11,15-pentamethyl-14-(6-methylhept-5-en-2-yl)-5-[(3,4,5-trihydroxyoxan-2-yl)oxy]tetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-7-en-9-yl)oxidanesulfonic acid (1)
(13R)-5-(3,4-dihydroxyphenyl)-6,9,17,19,21-pentahydroxy-13-(4-hydroxyphenyl)-4,12,14-trioxapentacyclo[11.7.1.0²,¹¹.0³,⁸.0¹⁵,²⁰]henicosa-2(11),3(8),5,9,15,17,19-heptaen-7-one (1)
(15Z)-Octadec-15-en-9,11,13-triynoic acid (1)
(1R)-1,4-bis({[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy})-3-hydroxy-5-(sulfooxy)cyclohexane-1-carboxylic acid (1)
(1R,16Z,24E,26E,28Z)-1,18,26,27-tetrahydroxy-19,30-dimethoxy-12-[1-(3-methoxy-4-oxocyclohexyl)propan-2-yl]-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.0⁴,⁹]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone (1)
(1R,16Z,24E,26E,28Z)-1,18-dihydroxy-12-[1-(4-hydroxy-3-methoxycyclohexyl)propan-2-yl]-19,30-dimethoxy-15,17,21,23,29-pentamethyl-35-methylidene-11,36-dioxa-4-azatricyclo[30.3.1.0⁴,⁹]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone (1)
(1R,2R,3R,11S,12S,14R,26R)-5,6',7',12-tetrahydroxy-6-methoxy-7,21,30-trimethyl-27-oxo-3',4'-dihydro-2'H-17,19,28-trioxa-24-thia-13,30-diazaspiro[heptacyclo[12.9.6.1³,¹¹.0²,¹³.0⁴,⁹.0¹⁵,²³.0¹⁶,²⁰]triacontane-26,1'-isoquinoline]-4(9),5,7,15(23),16(20),21-hexaen-22-yl acetate (1)
(1R,2S,3R,4R,5S,6R,7S)-1,3,4,5,7,8,9,10,10-Nonachlorotricyclo[5.2.1.0²,⁶]dec-8-ene (1)
(1R,6S,12R,15S)-5,5-Dimethyl-11,13-dioxatetracyclo[7.5.1.0¹,⁶.0¹²,¹⁵]pentadec-8-ene (1)
(1R,9S,18Z,24R)-12-[1-(4-chloro-3-hydroxycyclohexyl)prop-1-en-2-yl]-17-ethyl-1,14-dihydroxy-23,25-dimethoxy-13,19,21,27-tetramethyl-11,28-dioxa-4-azatricyclo[22.3.1.0⁴,⁹]octacos-18-ene-2,3,10,16-tetrone (1)
(1R,9S,18Z,24R)-12-[1-(4-chloro-3-methoxycyclohexyl)prop-1-en-2-yl]-17-ethyl-1,14-dihydroxy-13-(hydroxymethyl)-23,25-dimethoxy-19,21,27-trimethyl-11,28-dioxa-4-azatricyclo[22.3.1.0⁴,⁹]octacos-18-ene-2,3,10,16-tetrone (1)
(1S)-1,3,4-trihydroxy-5-(sulfooxy)cyclohexane-1-carboxylic acid (1)
(1S,16Z,24E,26E,28Z)-1,18-dihydroxy-12-{1-[4-(2-hydroxyethoxy)-3-methoxycyclohexyl]propan-2-yl}-15-(hydroxymethyl)-19,30-dimethoxy-17,21,23,29,35-pentamethyl-11,36-dioxa-4-azatricyclo[30.3.1.0⁴,⁹]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone (1)
(1S,16Z,24E,26E,28Z)-1,18-dihydroxy-12-{1-[4-(2-hydroxyethoxy)-5-methoxy-2-oxocyclohexyl]propan-2-yl}-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.0⁴,⁹]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone (1)
(1S,2R,10S,11S,14R,15R)-2,15-Dimethyl-14-[(2R)-6-methylheptan-2-yl]tetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-7-ene (1)
(1S,2S,10S,11S,15R)-14-(5,6-dimethylheptan-2-yl)-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadecane-5,17-diol (1)
(1S,2S,5R,7R,10S,11S,14R,15S,17S)-14-[(1R)-1,2-Dihydroxyethyl]-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadecane-5,14,17-triol (1)

Study type

Transcription profiling by array (5)
Unknown experiment type (1)
Methylation profiling by high throughput sequencing (1)
RNA-seq of coding RNA (1)

Release Date

2022 (84)
2018 (73)
2025 (69)
2021 (68)
2023 (64)
2024 (54)
2020 (52)
2016 (43)
2012 (42)
2015 (40)
2014 (35)
2017 (35)
2019 (34)
2013 (28)
2010 (27)
2011 (25)
2009 (19)
2008 (9)
2026 (8)
2006 (2)
2007 (1)

Lab affiliation

1Nutrient Metabolism & Signalling Laboratory, Metabolism, Diabetes and Obesity Program, Biomedicine Discovery Institute, Monash University, Victoria 3800, Australia. 2Department of Biochemistry and Molecular Biology, School of Biomedical Sciences, Faculty of Medicine, Nursing & Health Sciences, Monash University, Victoria 3800, Australia. (1)
Centre for Proteome Research, Institute of Systems, Molecular & Integrative Biology, University of Liverpool, Crown Street, Liverpool, L69 7ZB, U.K. (1)
Dana Farber Cancer Institute, Cancer Biology / Harvard Medical School, Biological Chemistry and Molecular Pharmacology (1)
Icahn School of Medicine at Mount Sinai (1)
Koch Institute for Integrative Cancer Research at MIT (1)

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The EZH2 inhibitor tazemetostat mitigates HIV immune evasion, reduces reservoir formation, and promotes durable CD8⁺ T-cell revitalization

Persistent HIV reservoirs in CD4⁺ T-cells impede efforts to cure HIV infection. We identified overexpression of enhancer of zeste homolog 2 (EZH2) in HIV-infected CD4⁺ T-cells that survive cytotoxic T lymphocyte (CTL) exposure, suggesting a mechanism of CTL resistance. Inhibition of EZH2 with the FD...

ORGANISM(S): Homo sapiens (Human)

2026-01-26 | PXD061146 | Pride

Untargeted metabolomics analyses and contaminant chemistry of Dreissenid mussels at the Maumee River Area of Concern in the Great Lakes

Bivalves serve as an ideal ecological indicator; hence, their use by the NOAA Mussel Watch Program to monitor environmental health. This study aimed to expand the baseline knowledge of using metabolic end points in environmental monitoring by investigating the dreissenid mussel metabolome in the ...

2024-06-03 | MTBLS6311 | MetaboLights

Effect of structural stability on endolysosomal degradation and T-cell reactivity of major shrimp allergen tropomyosin.

Not available

S-EPMC7687109 | biostudies-literature

Direct evidence for control of the pheromone-inducible prgQ operon of Enterococcus faecalis plasmid pCF10 by a countertranscript-driven attenuation mechanism.

Not available

S-EPMC2832536 | biostudies-literature

Immune profiling of patients with extranodal natural killer/T cell lymphoma treated with daratumumab.

Not available

S-EPMC11090967 | biostudies-literature

Polyfunctional CD4 T-cells correlating with neutralising antibody is a hallmark of COVISHIELD<sup>TM</sup> and COVAXIN<sup>®</sup> induced immunity in COVID-19 exposed Indians.

Not available

S-EPMC10502007 | biostudies-literature

Ecological transcriptomics of lake-type and riverine sockeye salmon (Oncorhynchus nerka) muscle tissue

We sampled lake-type and riverine sockeye in the pristine natural habitats of Aniakchak National Monument and Preserve, Alaska USA. Samples were taken on the same day and close proximite in time. We sampled 17 riverine individuals from Albert Johnson Creek and 13 individuals from Surprise Lake. cDNA...

ORGANISM(S): Oncorhynchus nerka

2011-09-09 | E-GEOD-31214 | biostudies-arrayexpress

Inhibition of mitochondrial complex I reverses NOTCH1-driven metabolic reprogramming in T-cell acute lymphoblastic leukemia.

Not available

S-EPMC9120040 | biostudies-literature

The molecular basis of complex neuropsychiatric disorders most likely involves many genes. In recent years, specific genetic variations influencing risk for schizophrenia and other neuropsychiatric disorders have been reported. We have used custom DNA microarrays and qPCR to investigate the expressi...

ORGANISM(S): Homo sapiens

2008-05-23 | E-GEOD-11546 | biostudies-arrayexpress

LFA-1-specific therapy prolongs allograft survival in rhesus macaques.

Not available

S-EPMC2994340 | biostudies-literature

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