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OtherGut health in multiple joint osteoarthritis: a multimodal investigation in humans and pet dogs
The Gut health in multiple joint osteoarthritis (MJOA) study leverages data from parallel community-based cohorts in humans and in pet dogs to elucidate the role of altered microbiota in MJOA. One hundred Johnston County Health Study human participants were 35 to 70 years of age at enrollment (2022-...
ORGANISM(S): Canis lupus familiaris 
2025-04-01 | GSE293105 | GEO
Transcriptomics"Calling Cards" for DNA-binding proteins in mammalian cells
The ability to chronicle transcription factor binding events throughout the development of an organism would facilitate mapping of transcriptional networks that control cell fate decisions. We describe a method for permanently recording protein-DNA interactions in mammalian cells. We endow transcri...
ORGANISM(S): Homo sapiens 
2011-12-31 | E-GEOD-34791 | biostudies-arrayexpress
GenomicsMultiplexed identification of the genomic targets of DNA-binding proteins
Transcription factors direct gene expression, and so there is much interest in mapping their genome-wide binding locations. M-BM- Current methods do not allow for the multiplexed analysis of TF binding, and this limits their throughput. We describe a novel method for determining the genomic target g...
ORGANISM(S): Saccharomyces cerevisiae 
2011-02-18 | E-GEOD-27381 | biostudies-arrayexpress
TranscriptomicsBulk RNA-seq from Trex1 KO in heart
Bulk RNA-seq data for Trex1 WT and KO mice from the heart. Used for manuscript in submission at Science Advances.
ORGANISM(S): Mus musculus 
2026-03-25 | E-MTAB-16524 | biostudies-arrayexpress
UnknownCarrier fluid temperature data in vertical ground heat exchangers with a varying pipe separation.
Not available
S-EPMC5996741 | biostudies-literature
MetabolomicsComparative Metabolomic Sampling of Upper and Lower Airways by Four Different Methods to Identify Biochemicals That May Support Bacterial Growth
Bacteria need nutrients from the host environment to survive, yet we know little about which biochemicals are present in the airways (the metabolome), which of these biochemicals are essential for bacterial growth and how they change with airway disease. The aims of this pilot study were to develop ...
2019-06-13 | MTBLS179 | MetaboLights
TranscriptomicsExpression data from tail skin in young (5 months) and old (30 months) CB6F1 mice
Background: Skin aging is associated with intrinsic processes that compromise structure of the extracellular matrix while promoting loss of functional and regenerative capacity. These processes are accompanied by a large-scale shift in gene expression, but underlying mechanisms are not understood an...
ORGANISM(S): Mus musculus 
2012-03-15 | E-GEOD-35322 | biostudies-arrayexpress
ProteomicsAre you also what Your Mother Eats? Distinct Proteomic Portrait as a Result of Maternal High-Fat Diet in the Cerebral Cortex of the Adult Mouse.
Background: Epidemiological studies suggest an association between maternal obesity and adverse neurodevelopmental outcomes in offspring. Objective: To compare the global proteomic portrait in the cerebral cortex between mice born to mothers on a high-fat or control diet who themselves were fed a h...
ORGANISM(S): Mus musculus (Mouse) 
2018-01-29 | PXD001540 | Pride
2d lc-ms/ms Proteomics Brain Obesity High-fat diet Cerebral cortex Itraq Maternal 
UnknownAssociations between the chemokine biomarker CCL2 and knee osteoarthritis outcomes: the Johnston County Osteoarthritis Project.
Not available
S-EPMC6098742 | biostudies-literature
TranscriptomicsArabidopsis thaliana embryo sac transcriptome
differential expression between wild-type pistils of Arabidopsis thaliana at late 11 to late 12 floral stages, and similar stage pistils of coatlique mutant which lacks a functional embryo sac
ORGANISM(S): Arabidopsis thaliana 
2007-10-02 | E-MEXP-1246 | biostudies-arrayexpress
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