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TranscriptomicsREST Couples Loss of Pluripotency with Neural Induction and Neural Differentiation
Neural differentiation of embryonic stem cells (ESCs) requires coordinated repression of the pluripotency regulatory programme and reciprocal activation of the neurogenic regulatory programme. Upon neural induction, ESCs rapidly repress expression of pluripotency genes followed by staged activation ...
ORGANISM(S): Mus musculus 
2011-12-08 | E-GEOD-34244 | biostudies-arrayexpress
TranscriptomicsRice perception of symbiotic arbuscular mychorrhizal fungi requires the karrikin receptor complex
In terrestrial ecosystems plants take up phosphate predominantly via association with arbuscular mycorrhizal fungi (AMF). We discovered that the loss of responsiveness to AMF in the rice deletion mutant hebiba is encoded by the alpha/beta fold hydrolase, DWARF 14 LIKE (D14L), which is one of the 26 ...
ORGANISM(S): Oryza sativa Japonica Group 
2016-03-14 | E-MTAB-4072 | biostudies-arrayexpress
TranscriptomicsDysregulation of REST-regulated coding and non-coding RNAs in a cellular model of HuntingtonM-bM-^@M-^Ys disease
Abstract - Huntingtin (Htt) protein interacts with many transcriptional regulators, with widespread disruption to the transcriptome in HuntingtonM-bM-^@M-^Ys disease (HD) brought about by altered interactions with the mutant Htt (muHtt) protein. Repressor Element-1 Silencing Transcription Factor (RE...
ORGANISM(S): Mus musculus 
2013-01-03 | E-GEOD-42107 | biostudies-arrayexpress
Genomicsena-DATASET-SFU-20-06-2017-22:32:50:620-88 - samples
This dataset consists of the exome sequencing data for 30 tumour and germline DNA pairs derived from relapsed/refractory DLBCL.
EGAD00001003395 | EGA
GenomicsGenetic landscape of relapsed DLBCL
Diffuse large B-cell lymphoma is a heterogenous malignancy that can arise de novo or can result from histologic transformation from indolent lymphomas. Considerable sequencing effort has been placed on determining the mutations that are common at the time of diagnosis in DLBCL but little is known ab...
EGAS00001001553 | EGA
TranscriptomicsDevelopment and Independent Validation of a Molecular Subtype in High Grade Serous Ovarian Cancer using Formalin Fixed Paraffin Embedded Tissue, Training set
High Grade Serous Ovarian Cancer (HGSOC) is a histopathological diagnosis and may represent multiple diseases at a molecular level. We investigated whether distinct molecular subgroups may influence treatment choice. The accompanying validation set of data has also been deposited in ArrayExpress und...
ORGANISM(S): Homo sapiens 
2020-12-21 | E-MTAB-2562 | biostudies-arrayexpress
UnknownTocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.
Not available
S-EPMC8084355 | biostudies-literature
UnknownDexamethasone in Hospitalized Patients with Covid-19.
Not available
S-EPMC7383595 | biostudies-literature
UnknownEffect of Hydroxychloroquine in Hospitalized Patients with Covid-19.
Not available
S-EPMC7556338 | biostudies-literature
UnknownEmpagliflozin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.
Not available
S-EPMC10957483 | biostudies-literature
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