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GenomicsAlzheimer's Disease Sequencing Project (ADSP)

The overarching goals of the ADSP are to: (1) identify new genomic variants contributing to increased risk of developing AD, (2) identify new genomic variants contributing to protection against developing AD, and (3) provide insight as to why individuals with known risk factor variants escape fro...

phs000572.v1.p1 | EGA
UnknownAdding Celecoxib With or Without Zoledronic Acid for Hormone-Naive Prostate Cancer: Long-Term Survival Results From an Adaptive, Multiarm, Multistage, Platform, Randomized Controlled Trial.
Not available
S-EPMC5455701 | biostudies-literature
MetabolomicsSimultaneously discovering the fate and biochemical effects of pharmaceuticals through untargeted metabolomics
Untargeted metabolomics is an established approach in toxicology for characterising endogenous metabolic responses to xenobiotic exposure. Detecting the xenobiotic and its biotransformation products as part of the metabolomics analysis provides an opportunity to simultaneously gain deep insights int...
2023-07-03 | MTBLS2746 | MetaboLights
TranscriptomicsHuman patient tumor-derived organoid characterization from bladder cancer patients that did not respond to chemotherapy
A total of 3 independently derived organoids were compared to patient tumor samples and patient normal samples to determine if the tumor-derived organoids represent the genomic landscape of the tumor from which they were derived.
ORGANISM(S): Homo sapiens 
2023-01-02 | E-MTAB-10353 | biostudies-arrayexpress
UnknownPrognostic risk score for patients with relapsed or refractory chronic lymphocytic leukaemia treated with targeted therapies or chemoimmunotherapy: a retrospective, pooled cohort study with external validations.
Not available
S-EPMC6620111 | biostudies-literature
ProteomicsEarly NK-cell and T-cell dysfunction marks progression to severe dengue in patients with obesity and healthy weight
Dengue is a mosquito-borne virus infection affecting half of the world’s population for which therapies are lacking. The role of T and NK-cells in protection/immunopathogenesis remains unclear for dengue for dengue. We performed a longitudinal phenotypic, functional and transcriptional analyses of T...
ORGANISM(S): Homo sapiens (Human) 
2025-05-21 | PXD061694 | Pride
Dengue Cd4+ t-cells Cd8+ t-cells Co-inhibitory receptors Cytotoxic cells Severe dengue biomarkers Nk-cells Type-i ifn 
UnknownFine mapping of genetic variants in BIN1, CLU, CR1 and PICALM for association with cerebrospinal fluid biomarkers for Alzheimer's disease.
Not available
S-EPMC3036586 | biostudies-literature
GenomicsEGAD00000000114
Whole transcriptome sequence data from 18 ovarian clear-cell carcinoma samples and one TOV21G ovarian clear-cell carcinoma cell line
EGAD00000000114 | EGA
GenomicsARID1A Mutations in Endometriosis-Associated Ovarian Carcinomas
We have sequenced the whole transcriptomes of 18 ovarian clear-cell carcinomas and 1 ovarian clear-cell carcinoma cell line and found somatic mutations in ARID1A (the AT-rich interactive domain 1A [SWI-like] gene) in 6 of the samples. ARID1A encodes BAF250a, a key component of the SWI–SNF chromati...
EGAS00000000075 | EGA
UnknownCommon genetic variants influence human subcortical brain structures.
Not available
S-EPMC4393366 | biostudies-literature
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