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UnknownCirculating tumor cells and response to chemotherapy in metastatic breast cancer: SWOG S0500.
Not available
S-EPMC4209100 | biostudies-literature
ProteomicsA systematic and scalable approach for dissecting the molecular 2 mechanisms of transcriptional regulation in bacteria
Gene regulation is one of the most ubiquitous processes in biology. And yet, while the catalogue of 15 bacterial genomes continues to expand rapidly, we remain ignorant about how almost all of the genes in 16 these genomes are regulated. Characterizing the molecular mechanisms by which regulatory se...
ORGANISM(S): Escherichia Coli 
2018-04-13 | PXD007892 | JPOST Repository
TranscriptomicsModel-driven multi-omic data analysis elucidates metabolic immunomodulators of macrophage activation
We used genome-scale modeling and multi-omics (transcriptomics, proteomics, and metabolomics) analysis to assess metabolic features that are critical for macrophage activation. We constructed a genome-scale metabolic network for the RAW 264.7 cell line to determine metabolic modulators of activation...
ORGANISM(S): Mus musculus 
2012-08-02 | E-GEOD-39785 | biostudies-arrayexpress
MetabolomicsSubcellular antibiotic visualization reveals a dynamic drug reservoir in infected macrophages
Tuberculosis, caused by the intracellular pathogen Mycobacterium tuberculosis, remains the world's deadliest infectious disease. Sterilizing chemotherapy requires at least 6 months of multidrug therapy. Difficulty visualizing the subcellular localization of antibiotics in infected host cells means t...
2020-12-07 | MTBLS959 | MetaboLights
UnknownIntensive vs Standard Treatment of Hyperglycemia and Functional Outcome in Patients With Acute Ischemic Stroke: The SHINE Randomized Clinical Trial.
Not available
S-EPMC6652154 | biostudies-literature
TranscriptomicsTranscription profiling of monkey thalamus
Nuclei of the mammalian thalamus are aggregations of neurons with unique architectures and input-output connections, yet the molecular determinants of their organizational specificity remain unknown. By comparing expression profiles of thalamus and cerebral cortex in adult rhesus monkeys we identifi...
ORGANISM(S): Macaca mulatta 
2008-06-15 | E-GEOD-6708 | biostudies-arrayexpress
TranscriptomicsmiR-155 regulates the ability of circulating cancer cells to colonize and establish metastasis
Abstract: Metastases are established through a complex multistep process by which tumor cells disseminate from the primary tumor and expand at distant sites. Traditionally, studies on metastasis have focused on proteins and protein-coding genes, but recently microRNAs (miRNAs) have achieved increasi...
ORGANISM(S): Homo sapiens 
2012-05-02 | E-GEOD-37719 | biostudies-arrayexpress
UnknownInternational Analysis of Electronic Health Records of Children and Youth Hospitalized With COVID-19 Infection in 6 Countries.
Not available
S-EPMC8196345 | biostudies-literature
MetabolomicsModel-driven multi-omic data analysis elucidates metabolic immunomodulators of macrophage activation
Macrophages are central players in immune response, manifesting divergent phenotypes to control inflammation and innate immunity through release of cytokines and other signaling factors. Recently, the focus on metabolism has been reemphasized as critical signaling and regulatory pathways of human pa...
2012-09-05 | MTBLS23 | MetaboLights
UnknownViral and Host Factors Are Associated With Mortality in Hospitalized Patients With COVID-19.
Not available
S-EPMC11175705 | biostudies-literature
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