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TranscriptomicsEffect of Medroxyprogesterone Acetate on Transcript Profile of Human Pregnant Myometrium
Context: Progesterone is important physiologically and therapeutically to maintain uterine quiescence during pregnancy. It acts in part through controlling myometrial gene expression. Objective: To use expression microarray and qRT-PCR validation to determine the changes in gene expression induced ...
ORGANISM(S): Homo sapiens 
2011-06-08 | E-GEOD-22961 | biostudies-arrayexpress
UnknownThe performance of the GAP model in patients with rheumatoid arthritis associated interstitial lung disease.
Not available
S-EPMC5506836 | biostudies-literature
TranscriptomicsComparative genomic hybridization of human perilobar nephrogenic rest and matching Wilms tumours to identify changes in DNA copy number associated with IGF-driven Wilms tumorigenesis
We have carried out microarray-based comparative genomic hybridisation (arrayCGH) on 50 perilobar nephrogenic rest and 25 matching Wilms tumours in order to identify changes in DNA copy number associated with IGF-driven Wilms tumorigenesis. All patient samples were formalin fixed-paraffin embedded a...
ORGANISM(S): Homo sapiens 
2009-02-25 | E-TABM-436 | biostudies-arrayexpress
TranscriptomicsSingle cell RNA-seq of isolated human foetal L/M-opsin cone photoreceptor populations labelled using the AAV2/9.pR2.1.GFP reporter
Human cone photoreceptors represent a rare cell population of the human retina and are largely outnumbered by other retinal cell types. Despite their rarity, cone photoreceptors are critical for optimal daylight vision and their loss has the greatest impact on sight during the progression of retinal...
ORGANISM(S): Homo sapiens 
2018-04-20 | E-MTAB-6058 | biostudies-arrayexpress
TranscriptomicsThe effect of PPARa siRNA on endothelial cells treated with fenofibrate
Fenofibrate is a synthetic ligand for the nuclear receptor peroxisome proliferator-activated receptor (PPAR) alpha, but there are reports that fenofibrate affects endothelial cells in PPARa-independent manner. In order to identify PPARa-dependently and PPARa-independently regulated transcripts we ge...
ORGANISM(S): Homo sapiens 
2009-08-24 | E-GEOD-15482 | biostudies-arrayexpress
TranscriptomicsCombined Chronic Toxicity and Carcinogenicity of Aerosol from a Heated Tobacco Product (microRNA data).
Smoking cessation is the most effective measure for reducing the risk of smoking-related diseases but switching to less harmful products (modified-risk tobacco products) can be an alternative for smokers who would otherwise not quit. In an 18-month chronic carcinogenicity/toxicity study in A/J mice ...
ORGANISM(S): Mus musculus 
2020-08-17 | E-MTAB-8541 | biostudies-arrayexpress
TranscriptomicsRegulation of gene expression during the onset of ligninolytic oxidation by Phanerochaete chrysosporium on colonized wood
The biodegradation of lignocellulose requires the disruption of its lignin, which shields the metabolically assimilable polysaccharides in this recalcitrant natural composite. Although a variety of microorganisms can attack lignocellulose, white rot basidiomycetes are uniquely efficient at this proc...
ORGANISM(S): Phanerochaete chrysosporium 
2015-09-16 | E-GEOD-69461 | biostudies-arrayexpress
TranscriptomicsRNA-seq of isolated human foetal and hiPSC L/M-opsin cone photoreceptor populations labelled using the AAV2/9.pR2.1.GFP reporter
The loss of cone photoreceptor cells, which are critical for optimal daylight vision, have the great impact on vision during retinal degenerations. Retinal differentiation of human induced pluripotent stem cell (hiPSC) sources could provide a renewable source of cone photoreceptors towards developin...
ORGANISM(S): Homo sapiens 
2018-04-20 | E-MTAB-6057 | biostudies-arrayexpress
TranscriptomicsComparative transcriptomics of Central Asian Vitis vinifera accessions reveals distinct defense strategies against powdery mildew
Grape powdery mildew (PM), caused by the biotrophic ascomycete Erysiphe necator, is a devastating fungal disease that affects most Vitis vinifera cultivars. We have previously identified a panel of V. vinifera accessions from Central Asia with partial resistance to PM that possess a Ren1-like local ...
ORGANISM(S): Vitis vinifera subsp. silvestris 
2015-07-20 | E-GEOD-67191 | biostudies-arrayexpress
UnknownCombinatorial transcription factor binding encodes cis-regulatory wiring of mouse forebrain GABAergic neurogenesis.
Not available
S-EPMC11753952 | biostudies-literature
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