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TranscriptomicsGene expression data from pilocytic astrocytoma tumour samples and normal cerebellum controls
Pilocytic astrocytomas (PA) are the most common brain tumor in pediatric patients and can cause significant morbidity, including chronic neurological deficiencies. They are characterized by activating alterations in the mitogen-activated protein kinase (MAPK) pathway, but little else is known about ...
ORGANISM(S): Homo sapiens 
2013-06-12 | E-GEOD-44971 | biostudies-arrayexpress
TranscriptomicsDNA methylation data from pilocytic astrocytoma tumor samples and normal cerebellum controls
Pilocytic astrocytomas (PA) are the most common brain tumor in pediatric patients and can cause significant morbidity, including chronic neurological deficiencies. They are characterized by activating alterations in the mitogen-activated protein kinase (MAPK) pathway, but little else is known about ...
ORGANISM(S): Homo sapiens 
2013-06-12 | E-GEOD-44684 | biostudies-arrayexpress
GenomicsNucleosome map of the IMR90 fibroblast cell line
We produced a map of nucleosome positions in IMR90 by sequencing the ends of MNase-digested chromatin fragments. IMR90 cells were grown in culture, about 1E6 cells were isolated and digested using micrococcal nuclease (MNase). Mononucleosomes were gel-selected and fragment ends were sequenced using ...
ORGANISM(S): Homo sapiens 
2011-04-01 | E-GEOD-21823 | biostudies-arrayexpress
UnknownIdentification of idiopathic inflammatory myopathy research cohorts using international classification of disease (ICD) codes: A systematic review.
Not available
S-EPMC12547942 | biostudies-literature
TranscriptomicsFrequent switching of Polycomb repressive marks and DNA hypermethylation in the PC3 prostate cancer cell line
Epigenetic reprogramming is commonly observed in cancer, and is hypothesized to involve multiple mechanisms, including DNA methylation and Polycomb repressive complexes (PRCs). Here we devise a new experimental and analytical strategy using customized high density tiling arrays to investigate coordi...
ORGANISM(S): Homo sapiens 
2008-08-07 | E-GEOD-12334 | biostudies-arrayexpress
TranscriptomicsCoordinated Chromatin Remodeling induced by Demethylation requires SRCAP mediated H2A.Z exchange [Methylation]
Genome wide DNA methylation profiling of RKO cells with combination treatments of non-target siRNA or SRCAP siRNA and PBS or 1uM 5-Aza-CdR treatment. The Illumina Infinium 27k Human DNA methylation Beadchip v1.2 was used to obtain DNA methylation profiles across 27,578 CpGs in treated RKO cells. Sam...
ORGANISM(S): Homo sapiens 
2013-01-01 | E-GEOD-26433 | biostudies-arrayexpress
GenomicsH2A.Z Mapping During G0/G1 and Mitosis
We report genome wide mapping of the histone variant H2A.Z during G0/G1 and mitosis in T24 bladder cancer cells. The results show that the broad enrichment pattern of H2A.Z near transcription start sites of active genes is maintained during mitosis. Furthermore, using H2A.Z localization to visuali...
ORGANISM(S): Homo sapiens 
2010-06-24 | E-GEOD-19568 | biostudies-arrayexpress
GenomicsA novel bivalent chromatin state exists at enhancers
We assess global chromatin accessibility following 5-Aza-CdR treatment of HCT116 cells Simultaneous genome-wide mapping of DNA methylation and nucleosome occupancy of HCT116 cells
ORGANISM(S): Homo sapiens 
2016-06-02 | E-GEOD-68046 | biostudies-arrayexpress
TranscriptomicsCoordinated Chromatin Remodeling induced by Demethylation requires SRCAP mediated H2A.Z exchange [expression]
Genome wide gene expression profiling of RKO cells with combination treatments of non-target siRNA or SRCAP siRNA and PBS or 1uM 5-Aza-CdR treatment. The sample treated with non target siRNA and PBS serves as control sample. Total RNA obtained from isolated RKO cells.
ORGANISM(S): Homo sapiens 
2013-01-01 | E-GEOD-26684 | biostudies-arrayexpress
UnknownRelationships between cortical myeloarchitecture and electrophysiological networks.
Not available
S-EPMC5127325 | biostudies-literature
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