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GenomicsTemporal uncoupling of the DNA methylome and transcriptional repression during embryogenesis
DNA methylation is a tightly regulated epigenetic mark associated with transcriptional repression. Next-generation sequencing of purified methylated DNA obtained from early Xenopus tropicalis embryos demonstrates that this genome is heavily methylated during blastula and gastrula stages. Although DN...
ORGANISM(S): Xenopus (Silurana) tropicalis 
2011-06-23 | E-GEOD-23913 | biostudies-arrayexpress
UnknownBacille Calmette-Guerin vaccination to prevent febrile and respiratory illness in adults (BRACE): secondary outcomes of a randomised controlled phase 3 trial.
Not available
S-EPMC11106519 | biostudies-literature
UnknownBacillus Calmette-Guerin vaccination for protection against recurrent herpes labialis: a nested randomised controlled trial.
Not available
S-EPMC10500555 | biostudies-literature
UnknownBCG vaccination to reduce the impact of COVID-19 in healthcare workers: Protocol for a randomised controlled trial (BRACE trial).
Not available
S-EPMC8557250 | biostudies-literature
TranscriptomicsTranscriptional profiles of macrophages in resolving inflammation
We have performed a comprehensive transcriptional analysis of specific monocyte and macrophage (MM-CM-^X) subsets during an acute self-resolving inflammatory insult. Following initial induction of acute inflammation, tissue resident (Resident) MM-CM-^X are rapidly M-bM-^@M-^XclearedM-bM-^@M-^Y from ...
ORGANISM(S): Mus musculus 
2014-05-09 | E-GEOD-28621 | biostudies-arrayexpress
TranscriptomicsA new Rrf2 repressor family member, SaiR, controls transcription of spxA2 encoding a regulator of the oxidative stress response in Bacillus anthracis.
Spx, a member of the ArsC (arsenate reductase) protein family, is highly conserved in Gram-positive bacteria, where it interacts with RNA polymerase to activate transcription in response to toxic oxidants.  In Bacillus anthracis, resistance to oxidative stress requires the activity of two paralogou...
ORGANISM(S): Bacillus anthracis 
2014-05-21 | E-GEOD-57851 | biostudies-arrayexpress
UnknownSafety and immunogenicity of one versus two doses of the COVID-19 vaccine BNT162b2 for patients with cancer: interim analysis of a prospective observational study.
Not available
S-EPMC8078907 | biostudies-literature
UnknownSpecific and off-target immune responses following COVID-19 vaccination with ChAdOx1-S and BNT162b2 vaccines-an exploratory sub-study of the BRACE trial.
Not available
S-EPMC11058726 | biostudies-literature
UnknownManagement of Patients with Advanced Prostate Cancer. Part I: Intermediate-/High-risk and Locally Advanced Disease, Biochemical Relapse, and Side Effects of Hormonal Treatment: Report of the Advanced Prostate Cancer Consensus Conference 2022.
Not available
S-EPMC7614721 | biostudies-literature
UnknownEffect of Angiotensin-Converting Enzyme Inhibitor and Angiotensin Receptor Blocker Initiation on Organ Support-Free Days in Patients Hospitalized With COVID-19: A Randomized Clinical Trial.
Not available
S-EPMC10326520 | biostudies-literature
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