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UnknownPlasma glycomics predict cardiovascular disease in patients with ART-controlled HIV infections.
Not available
S-EPMC6338643 | biostudies-literature
MetabolomicsTargeted metabolomic analysis in hepatic extracts, serum, and urine of female mice gavaged with TCDD every 4 days for 28 days
TCDD is an environmental contaminant that elicits a number of hepatic effects including fat accumulation, inflammation, and fibrosis that can progress to hepatocellular carcinoma. RNA-Seq and targeted metabolomics were integrated with complementary dioxin response element (DRE) location and aryl hyd...
2017-02-02 | MTBLS225 | MetaboLights
MetabolomicsNon-targeted multimodal metabolomics and lipidomics data from ovine rumen fluid fractions

From an animal production and health perspective, our understanding of the metabolites in ruminant biofluids, particularly rumen fluid across different host species is poorly understood. Metabolomics is a powerful and sensitive approach for investigating low molecular weight metabolite profiles p...

2021-08-23 | MTBLS1717 | MetaboLights
MetabolomicsAntiviral metabolite 3'-Deoxy-3',4'-didehydro-cytidine is detectable in serum and identifies acute viral infections including COVID-19

BACKGROUND: There is a critical need for rapid viral infection diagnostics to enable prompt case identification in pandemic settings and support targeted antimicrobial prescribing.

METHODS: Using untargeted high-resolution liquid chromatography coupled with...

2022-02-10 | MTBLS718 | MetaboLights
TranscriptomicsLIN28 binds messenger RNAs at GGAGA motifs and regulates splicing factor abundance (HTS)
LIN28 is a conserved RNA binding protein implicated in pluripotency, reprogramming and oncogenesis. Previously shown to act primarily by blocking let-7 microRNA (miRNA) biogenesis, here we elucidate distinct roles of LIN28 regulation via its direct messenger RNA (mRNA) targets. Through cross-linking...
ORGANISM(S): Homo sapiens 
2012-09-10 | E-GEOD-39872 | biostudies-arrayexpress
TranscriptomicsLIN28 binds messenger RNAs at GGAGA motifs and regulates splicing factor abundance
This SuperSeries is composed of the following subset Series: GSE39855: LIN28 binds messenger RNAs at GGAGA motifs and regulates splicing factor abundance (splicing array) GSE39872: LIN28 binds messenger RNAs at GGAGA motifs and regulates splicing factor abundance (HTS) Refer to individual Series
ORGANISM(S): Homo sapiens 
2012-09-10 | E-GEOD-39873 | biostudies-arrayexpress
TranscriptomicsGene expression data from medulloblastoma tumor samples
Smoothened (SMO)-inhibitors recently entered clinical trials for sonic-hedgehog driven medulloblastoma (SHH-MB). Clinical response appears highly variable. To understand the mechanism(s) of primary resistance and to identify pathways co-operating with aberrant SHH-signaling, we sequenced a large coh...
ORGANISM(S): Homo sapiens 
2014-06-02 | E-GEOD-49243 | biostudies-arrayexpress
TranscriptomicsHuman bronchial epithelial cells_Passage 3 vs. passage 0
Squamous metaplasia is common in smokers and is associated with airway obstruction in chronic obstructive pulmonary disease (COPD). A major mechanism of airway obstruction in COPD is thickening of the small airway walls. We asked whether squamous metaplasia actively contributes to airway wall thicke...
ORGANISM(S): Homo sapiens 
2007-08-30 | E-GEOD-7557 | biostudies-arrayexpress
UnknownMetabolic reprograming and increased inflammation by cadmium exposure following early-life respiratory syncytial virus infection-the involvement of protein S-palmitoylation.
Not available
S-EPMC10823773 | biostudies-literature
TranscriptomicsPriming defense genes and metabolites in hybrid poplar by the green leaf volatile cis-3-hexenyl acetate
• Herbivore-induced plant volatiles (HIPVs), in addition to attracting natural enemies of herbivores, can serve a signaling function within plants by acting as wound signals that induce or prime defenses. However, particularly in woody plants, which compounds within HIPV blends are capable of act...
ORGANISM(S): Populus x canadensis 
2010-05-25 | E-GEOD-11955 | biostudies-arrayexpress
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