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ProteomicsStructural proteomics defines a sequential priming mechanism for the progesterone receptor (HDX-MS)
The progesterone receptor (PR) is a steroid-responsive nuclear receptor with two isoforms: PR-A and PR-B. Disruption of PR-A:PR-B signaling is associated with breast cancer through interactions with oncogenic co-regulatory proteins (CoRs). However, molecular details of isoform-specific PR-CoR intera...
ORGANISM(S): Homo sapiens (Human) 
2025-04-07 | PXD056400 | Pride
Hydrogen-deuterium exchange Progesterone receptor Structural proteomics Hdx 
ProteomicsTime-resolved Global and Chromatin Proteomics during Herpes Simplex Virus (HSV-1) Infection
Herpes simplex virus (HSV-1) lytic infection results in global changes to the host cell proteome and the proteins associated with host chromatin. We present a system level characterization of proteome dynamics during infection by performing a multi-dimensional analysis during HSV-1 lytic infection o...
ORGANISM(S): Homo sapiens (Human) Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1) 
2017-02-10 | PXD005467 | Pride
Post-translational modifications (ptms) Viral life cycle Chromatin dynamics Herpes simplex virus (hsv-1) infection Lytic infection Phosphoproteomics Histone modifications 
UnknownGWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19.
Not available
S-EPMC10208981 | biostudies-literature
UnknownChildhood Asthma Incidence, Early and Persistent Wheeze, and Neighborhood Socioeconomic Factors in the ECHO/CREW Consortium.
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S-EPMC9127710 | biostudies-literature
UnknownGlobal hospital-based disease management of acute diverticulitis: a prospective, international cohort study.
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S-EPMC12512976 | biostudies-literature
UnknownTemporal changes in the epidemiology, management, and outcome from acute respiratory distress syndrome in European intensive care units: a comparison of two large cohorts.
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S-EPMC7906083 | biostudies-literature
UnknownThe global, regional, and national burden of cancer, 1990-2023, with forecasts to 2050: a systematic analysis for the Global Burden of Disease Study 2023.
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S-EPMC12687902 | biostudies-literature
UnknownRelationship Between Severity of Ischemia and Coronary Artery Disease for Different Stress Test Modalities in the ISCHEMIA Trial.
Not available
S-EPMC11658795 | biostudies-literature
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