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Defects in homocysteine and folate metabolism are associated with increased risks for neural tube and congenital heart defects, cardiovascular disease and stroke, cancers, and neurodegeneration. In many but not all cases, dietary supplementation with folate significantly reduces the severity and in...
ORGANISM(S): Mus musculus 
Liver and Spleen RNA samples were compared between A/J and C57BL/6 mice and between C57BL/6 wildtype and TNF knockouts at five time points following Trypanosoma Congolense infection
ORGANISM(S): Mus musculus 
Liver and Spleen RNA samples were compared between A/J and C57BL/6 mice and between C57BL/6 wildtype and TNF knockouts at five time points following Trypanosoma Congolense infection
ORGANISM(S): Mus musculus 
A comparison of lung tissue among both sexes and three different strains(A/J, C57BL/6, DBA) of mouse
ORGANISM(S): Mus musculus 
A comparison of lung tissue among both sexes and three different strains(A/J, C57BL/6, DBA) of mouse
ORGANISM(S): Mus musculus 

INTRODUCTION: The dysregulation of cortisol secretion has been associated with a number of mental health and mood disorders. However, diagnostics for mental health and mood disorders are behavioral and lack biological contexts.

OBJECTIVES: The goal of this ...

2021-09-23 | MTBLS1206 | MetaboLights
This SuperSeries is composed of the following subset Series: GSE9242: Dietary folate depletion and repletion in A/J and C57BL/6J mice GSE9243: Dietary folate depletion and repletion in C57BL/6J mice, ApoE knockout mice, and choline supplemented C57BL/6J mice Keywords: SuperSeries Refer to individual...
ORGANISM(S): Mus musculus 
Purpose: The clinical use of MEK inhibitors in uveal melanoma is limited by the rapid acquisition of resistance. The current study has used multi-omics approaches and drug screens to identify the pan-HDAC inhibitor panobinostat as an effective strategy to limit MEK inhibitor resistance. Experimental...
ORGANISM(S): Homo sapiens (Human) 
2020-05-26 | PXD013988 | Pride
To evaluate the effect of genetic background on the immune response to streptococcal infection, eight genetically diverse strains of mice (129/SvImJ, A/J, Balb/cJ, C3H/HeJ, C57BL/6J, Cast/EI, DBA/2J, and FVB/NJ) were infected with three doses of Streptococcus zooepidemicus (500, 5,000, or 50,000 col...
ORGANISM(S): Mus musculus 
To evaluate the effect of genetic background on the immune response to streptococcal infection, eight genetically diverse strains of mice (129/SvImJ, A/J, Balb/cJ, C3H/HeJ, C57BL/6J, Cast/EI, DBA/2J, and FVB/NJ) were infected with three doses of Streptococcus zooepidemicus (500, 5,000, or 50,000 col...
ORGANISM(S): Mus musculus 
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