Sort   by:  
 Page size 
UnknownComparison of prokaryotic community structure from Mediterranean and Atlantic saltern concentrator ponds by a metagenomic approach.
We analyzed the prokaryotic community structure of a saltern pond with 21% total salts located in Isla Cristina, Huelva, Southwest Spain, close to the Atlantic ocean coast. For this purpose, we constructed a metagenome (designated as IC21) obtained by pyrosequencing consisting of 486 Mb with an aver...
S-EPMC4021199 | biostudies-literature
UnknownFrom metagenomics to pure culture: isolation and characterization of the moderately halophilic bacterium Spiribacter salinus gen. nov., sp. nov.
Recent metagenomic studies on saltern ponds with intermediate salinities have determined that their microbial communities are dominated by both Euryarchaeota and halophilic bacteria, with a gammaproteobacterium closely related to the genera Alkalilimnicola and Arhodomonas being one of the most predo...
S-EPMC4054224 | biostudies-literature
UnknownHepatitis C virus genetic variability and evolution.
Hepatitis C virus (HCV) has infected over 170 million people worldwide and creates a huge disease burden due to chronic, progressive liver disease. HCV is a single-stranded, positive sense, RNA virus, member of the Flaviviridae family. The high error rate of RNA-dependent RNA polymerase and the pres...
S-EPMC4411526 | biostudies-literature
UnknownThe biochemical pattern defines MASLD phenotypes linked to distinct histology and prognosis.

Background

MASLD can manifest as hepatocellular damage, which can result in mild elevation of aminotransferases. However, in some patients, MASLD presents with cholestatic pattern.

Objective

To assess the impact of the biochemical pattern on the natural course of MASLD, including live...
S-EPMC11217049 | biostudies-literature
UnknownAll-oral direct-acting antiviral therapy against hepatitis C virus (HCV) in human immunodeficiency virus/HCV-coinfected subjects in real-world practice: Madrid coinfection registry findings.
We evaluated treatment outcomes in a prospective registry of human immunodeficiency virus/hepatitis C virus (HCV)-coinfected patients treated with interferon-free direct-acting antiviral agent-based therapy in hospitals from the region of Madrid between November 2014 and August 2016. We assessed sus...
S-EPMC6055848 | biostudies-literature
TranscriptomicsChIP-chip by array of fission yeast wild type and meu5 mutants
RNA polymerase II ChIP-chip in wild type and meu5 mutants
ORGANISM(S): Schizosaccharomyces pombe 
2011-01-01 | E-TABM-993 | biostudies-arrayexpress
TranscriptomicsRibonucleoprotein immunoprecipitation of Schizosaccharomyces pombe cells using the RNA-binding protein Meu5
Ribonucleoprotein immunoprecipitation microarray (RIp-chip) study using the RNA-binding protein Meu5 from the fission Schizosaccaromyces pombe
ORGANISM(S): Schizosaccharomyces pombe 
2011-01-01 | E-TABM-932 | biostudies-arrayexpress
ProteomicsRAS-p110α signalling pathway in macrophages and its impact on both the initiation and resolution of inflammation
This study presents a secretome analysis of bone marrow-derived macrophages (BMDMs) from wild-type (WT) and RAS-p110α-disrupted macrophages. Samples were collected under both unstimulated conditions and during phagocytosis of apoptotic cells. The aim was to identify differential regulatory factors s...
ORGANISM(S): Mus musculus (Mouse) 
2025-04-28 | PXD057794 | Pride
Proteomics Inflammation Macrophages Ras-pi3k Lc-ms/ms 
TranscriptomicsTranscription profiling of Salmonella enterica serovar Typhimurium hha ydgT mutants
transcriptomic analysis of hha ydgT mutants in Salmonella enterica serovar Typhimurium
ORGANISM(S): Salmonella typhimurium 
2008-01-01 | E-MEXP-1303 | biostudies-arrayexpress
MetabolomicsPathogenic NLRP3 mutants form constitutively active inflammasomes resulting in immune-metabolic limitation of IL-1β production

BACKGROUND: Cryopyrin-Associated Periodic Syndrome (CAPS) is an autoinflammatory condition consequence of monoallelic variants in the NLRP3 gene that exacerbate IL-1β production. These variants are gain-of-function, but the exact regulatory mechanism of the NLRP3 CAPS-inflammasom...

2024-01-09 | MTBLS7872 | MetaboLights
Sort   by:  
 Page size