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TranscriptomicsPlatypus fibroblast and ovary transcriptomes
As a result of sex chromosome differentiation from ancestral autosomes, male mammalian cells only contain one X chromosome. It has long been hypothesized that X-linked gene expression levels have become doubled in males to restore dosage balance between the X and autosomes, and that the resulting X ...
ORGANISM(S): Ornithorhynchus anatinus 
2012-05-16 | E-GEOD-36120 | biostudies-arrayexpress
TranscriptomicsIGR_CREMEC_CGH_STYDY_LL
Patient-derived xenograft models are considered to represent the heterogeneity of human cancers and might be more relevant preclinical models to evaluate effective therapeutic agents. Our consortium joins efforts to extensively develop and characterize a new collection of patient-derived colorectal ...
ORGANISM(S): Homo sapiens 
2012-07-27 | E-MTAB-992 | biostudies-arrayexpress
ProteomicsDissecting the molecular mechanisms of mother-to-egg immune protection in the mealworm beetle Tenebrio molitor
In a number of species, individuals exposed to pathogens can mount an immune response and transmit this immunological experience to their offspring, thereby protecting them against persistent threats. Such vertical transfer of immunity, named trans-generational immune priming (TGIP), has been descri...
ORGANISM(S): Tenebrio molitor 
2020-10-08 | PXD018772 | Pride
Trans-generational immune priming  invertebrate immunity  host-pathogens interaction  molecular mechanisms  omics  antimicrobial peptides 
TranscriptomicsCIT - Homo sapiens - APUP - Genomic aberrations in Lung Adenocarcinoma in Never Smokers
41 lung adenocarcinoma from never-smokers hybridized on Illumina SNP arrays on 13 HumanCNV370-Quadv3 chips. High-resolution array comparative genomic hybridization analysis of lung adenocarcinoma in 41 never smokers for identification of new minimal common regions (MCR) of gain or loss. The SNP arr...
ORGANISM(S): Homo sapiens 
2011-07-28 | E-TABM-1169 | biostudies-arrayexpress
TranscriptomicsCohesin association to replication sites depends on Rad50 and promotes fork restart
The cohesin complex holds together newly-replicated chromatids and is involved in diverse pathways that preserve genome integrity. We show that in budding yeast, cohesin is transiently recruited to active replication origins and it spreads along DNA as forks progress. When DNA synthesis is impeded, ...
ORGANISM(S): Saccharomyces cerevisiae W303 
2012-10-01 | E-GEOD-39078 | biostudies-arrayexpress
TranscriptomicsIGR_CREMEC_GEX_STUDY_LL
Patient-derived xenograft models are considered to represent the heterogeneity of human cancers and might be more relevant preclinical models to evaluate effective therapeutic agents. Our consortium joins efforts to extensively develop and characterize a new collection of patient-derived colorectal ...
ORGANISM(S): Homo sapiens 
2012-07-27 | E-MTAB-991 | biostudies-arrayexpress
Transcriptomicsoverview of gene expression dynamics during sheep early ovarian folliculogenesis
Separate transcription profiling of oocytes and granulosa cells for each follicle stage: primordial (PD), primary (PM), secondary (SC) follicles and the small antral stage (SA) obtained by Laser Capture Microdissection (LCM) and RNAseq. The purpose of this study was to describe global gene expressi...
ORGANISM(S): Ovis aries 
2014-01-29 | E-MTAB-1587 | biostudies-arrayexpress
UnknownTreat stroke to target trial design: First trial comparing two LDL targets in patients with atherothrombotic strokes.
Not available
S-EPMC6960693 | biostudies-literature
TranscriptomicsRNA-seq of 6 tissues from Monodelphis domestica to investigate the evolution of gene expression levels in mammalian organs
This experiment contains the subset of data corresponding to gray short-tailed opossum RNA-Seq data from experiment E-GEOD-30352 (http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-30352/), which goal is to understand the dynamics of mammalian transcriptome evolution. To study mammalian transcript...
ORGANISM(S): Monodelphis domestica 
2011-10-12 | E-MTAB-3719 | biostudies-arrayexpress
TranscriptomicsRNA-seq of 6 tissues from Homo sapiens to investigate the evolution of gene expression levels in mammalian organs
This experiment contains the subset of data corresponding to human RNA-Seq data from experiment E-GEOD-30352 (http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-30352/), which goal is to understand the dynamics of mammalian transcriptome evolution. To study mammalian transcriptome evolution at hig...
ORGANISM(S): Homo sapiens 
2011-10-12 | E-MTAB-3716 | biostudies-arrayexpress
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