Background: Hypertensive nephrosclerosis is one of the most frequent causes of chronic kidney failure. Proteome analysis potentially improves the pathophysiological understanding and diagnostic precision of this disorder. In the present exploratory study, we investigated experimental nephrosclerosis...
Balb/cJ and C57BL/6J were subjected to either 0.5µg/kg/min angiotensin II, 3% sodium diet, or the combination. Sham operated animals receiving a 0.3% sodium normal diet were used as controls.