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ProteomicsProteomic profiling of scaffold-guided bone healing in type 2 diabetes rat model with critical-sized bone defect
Type 2 diabetes mellitus significantly impairs bone healing, with delayed regeneration observed in over 60% of diabetic patients. This study investigated the molecular mechanisms underlying diabetes-associated compromised regeneration using time-resolved proteome profiling of critical-sized femoral ...
ORGANISM(S): Rattus norvegicus (Rat) 
2026-04-16 | PXD071312 | Pride
ProteomicsDysregulated proteases homoeostasis in primary focal segmental glomerulosclerosis
Focal segmental glomerulosclerosis (FSGS) represents a pattern of injuries seen in histopathology rather than a distinct disease. Presently, FSGS is categorized into primary, genetic, and secondary types, although these subcategories probably encompass significantly diverse pathogeneses. Here, we pe...
ORGANISM(S): Homo sapiens (Human) 
2026-04-13 | PXD058875 | Pride
Serpina1 Pfsgs Proteomics Tmt Par1 Proteases Zebrafish Dda 
ProteomicsProteomic response to heat shock in males and females of a Baikal endemic amphipod Eulimnogammarus cyaneus (Dyb. 1874) (Crustacea: Amphipoda)
In this project we aimed to establish a proteome-based pipeline for a non-model Baikal endemic amphipod species Eulimnogammarus cyaneus (Dybowsky, 1874). We used next-generation transcriptome sequencing to create a database for protein identification and investigated the proteome of E. cyaneus with ...
ORGANISM(S): Eulimnogammarus cyaneus 
2020-11-19 | PXD013237 | Pride
Heat shock Baikal Eulimnogammarus cyaneus Intersexual difference Amphipoda 
ProteomicsProtein composition of circulating exosomes depend on tuberculosis disease state
Tuberculosis (TB) is a contagious disease that is a primary cause of mortality and illness in around a quater of the world' population particular in low income nations. The disease most commonly affects lung, but pathogens can also be found in other parts of the body. Mycobacterium tuberculosis (Mtb...
ORGANISM(S): Homo sapiens (Human) Mycobacterium tuberculosis 
2022-05-20 | PXD030883 | Pride
Tuberculosis Apolipoproteins Exosomes Plasma Immunoglobulins Mycobacterium tuberculosis 
ProteomicsA Novel Two-Step Proteome Extraction Protocol for Bone Tissue: Enhancing Low-Abundance Protein Detection and Multi-Omics Compatibility
Bone metabolism is a dynamic process involving osteoblasts, osteoclasts, and osteocytes, which maintain skeletal integrity through continuous remodelling. Disruptions in this homeostasis – caused by mineral or hormonal imbalances, systemic metabolic or inflammatory conditions, or genetic predisposit...
ORGANISM(S): Rattus norvegicus (Rat) 
2025-08-13 | PXD056459 | Pride
Proteome extraction Rat Bone tissue Multi-omics Comparison 
ProteomicsH.pylori 26695 - Whole organism, SC (Müller,j_proteomics,2013)
abundance based on Spectral counting, Interaction consistency score: 10.3, Coverage: 93
ORGANISM(S): 85962 
2013-00-00 | 3620106669 | PAXDB
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