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Kallikrein-related peptidases 4, 5, 6 and 7 regulate tumor-associated factors in serous ovarian cancer
Progesterone (P4) acting through its cognate receptor, the progesterone receptor (PR), plays an important role in uterine physiology. The PR knockout (PRKO) mouse has demonstrated the importance of the P4-PR axis in the regulation of uterine function. To define the molecular pathways regulated by P4...
ORGANISM(S): Mus musculus 
Background: Tissue kallikrein-related peptidases 4, 5, 6 and 7 (KLK4-7) strongly increase the malignancy of ovarian cancer cells. By further deciphering the downstream effectors of KLK4-7, we aimed at finding new potential prognostic biomarkers and treatment targets for ovarian cancer patients. KLK4...
ORGANISM(S): Homo sapiens 
2018-12-26 | GSE109261 | GEO
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