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We report age-differential synaptic plasticity deficits associated with cognitive inflexibility and CaMKIIa hyperactivity in Adnp-mutant mice. These mice show impaired and inflexible contextual learning and memory additional to social and anxiety-related deficits in adults long after a marked decrea...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
Autism spectrum disorders (ASD) represent neurodevelopmental disorders characterized by social deficits, repetitive behaviors, and various comorbidities, including epilepsy. ANK2, which encodes a neuronal scaffolding protein, is frequently mutated in ASD, but its in vivo functions and disease-relate...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2023-03-19 | MSV000091510 | MassIVE
We propose and demonstrate a systematic approach designed to combine stringent criteria for claims of missing protein (MP) identification with extensive annotation as critical components of the discovery and functional validation of MPs.
ORGANISM(S): Homo sapiens (Human) 
2018-01-05 | PXD004723 | Pride
This study aims to elucidate the cellular mechanisms underlying the secretion of factor B (CFB), recognized for its dual role as an early biomarker of pancreatic ductal adenocarcinoma (PDAC) and as the initiating substrate for the alternative complement pathway (ACP), a crucial component of the inna...
ORGANISM(S): Homo sapiens (Human) 
2024-05-21 | PXD047043 | Pride
PTPδ, encoded by PTPRD, is implicated in various neurological, psychiatric, and neurodevelopmental disorders, but the underlying mechanisms remain unclear. PTPδ trans-synaptically interacts with multiple postsynaptic adhesion molecules, which involves its extracellular alternatively spliced mini-exo...
ORGANISM(S): Mus musculus (Mouse) 
2025-04-01 | PXD053554 | Pride
LC-MSe data of 13 Taraxacum species (whole plant body) extracts for analyzing their chemical diversity, including 8 QC samples (mixture of all the samples in same conc.)
ORGANISM(S): Taraxacum Platycarpum (ncbitaxon:170727) Taraxacum Officinale (ncbitaxon:50225) Taraxacum Ohwianum Taraxacum Coreanum (ncbitaxon:1041103) Taraxacum Mongolicum (ncbitaxon:90037) 
2020-02-06 | MSV000084931 | GNPS
We sequenced mRNA from mouse EML cell line under Kai1 knockdown or Kai1 overexpressing condition. KAI1 belongs to tetraspanin superfamily and is known as suppressor of tumor metastasis. Examination of mRNA levels in wildtype (WT) and KAI1 knockdown EML cells were generated by deep sequencing, in dup...
ORGANISM(S): Mus musculus 
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