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TranscriptomicsTranscription profiling of mouse liver from wild type (WT), RORalphasg/sg, RORgamma-/-, and double knockout animals reveals a regulatory role for RORalpha and RORgamma in Phase I and Phase II Metabolism
Retinoid-related orphan receptors RORalpha and RORgamma are both expressed in liver; however, their physiological functions have not yet been clearly defined. RORalpha1 and RORgamma1, but not RORalpha4, show an oscillatory pattern of expression during circadian rhythm. To obtain insight into the phy...
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-7564 | biostudies-arrayexpress
MetabolomicsLinking genetic, metabolic and phenotypic diversity 1 among S. cerevisiae strains using multi-omics associations
The selection of bioengineering platform strains and engineering strategies to improve the stress resistance of Saccharomyces cerevisiae remains a pressing need in bio-based chemical production. Thus, a systematic effort to exploit the genotypic and phenotypic diversity to boost yeast’s industrial v...
2019-01-16 | MTBLS780 | MetaboLights
ProteomicsThe BPAN disease protein WDR45 forms condensates with Caprin-1 to regulate stress granule disassembly
Beta-propeller protein-associated neurodegeneration (BPAN) is a rare X-linked neurodegenerative disorder primarily caused by mutations in the WD repeat domain 45 (WDR45) gene. While WDR45 has traditionally been linked to autophagy, our study uncovers a previously unrecognized role for WDR45 as a cri...
ORGANISM(S): Homo Sapiens 
2025-04-14 | PXD062911 |
UnknownThalamocortical functional connectivity in patients with insomnia using resting-state fMRI.
Not available
S-EPMC8612467 | biostudies-literature
GenomicsORC precisely positions nucleosomes at origins of replication
The budding yeast genome is marked by 250-350 origins of DNA replication. These origins are bound by the origin recognition complex (ORC) throughout the cell cycle. ORC has known DNA binding sequence preferences which, though necessary for binding, are not sufficient to fully specify a genomic locus...
ORGANISM(S): Saccharomyces cerevisiae 
2010-03-19 | E-GEOD-16926 | biostudies-arrayexpress
UnknownCarbamidocyclophanes F and G with Anti-Mycobacterium tuberculosis Activity from the Cultured Freshwater Cyanobacterium Nostoc sp.
Not available
S-EPMC4161986 | biostudies-literature
MetabolomicsComparative metabolomic analysis of exudates of microcystin-producing and microcystin-free Microcystis aeruginosa strains

Cyanobacterial harmful algal blooms (cHABs) dominated by Microcystis aeruginosa threaten the ecological integrity and beneficial uses of lakes globally. In addition to producing hepatotoxic microcystins (MC), M. aeruginosa exudates (MaE) contain various compounds with demonstrat...

2023-01-16 | MTBLS6603 | MetaboLights
UnknownAssociation Between Subjective-Objective Discrepancy of Sleeping Time and Health-Related Quality of Life: A Community-Based Polysomnographic Study.
Not available
S-EPMC9064942 | biostudies-literature
UnknownSocial relationships enhance the time spent eating and intake of a novel diet in pregnant Hanwoo (Bos taurus coreanae) heifers.
Not available
S-EPMC5426355 | biostudies-literature
UnknownGenomic selection strategies to overcome genotype by environment interactions in biosecurity-based aquaculture breeding programs.
Not available
S-EPMC11752716 | biostudies-literature
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