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ORGANISM(S): Bos taurus (Bovine) 
2009-12-01 | PRD000140 | Pride
ASFV poses a continuing threat to the pig industry in Europe as broadly applicable vaccines are not available. Variations within the ASFV genome resulted in the emergence of attenuated strains with low or moderate virulence, however, the molecular basis of the differences in virulence is not known. ...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2023-01-05 | PXD036402 | Pride
Respiratory tract epithelium infection is considered crucial for airborne transmission of Nipah virus (NiV). Knowledge about infection dynamics and host responses to NiV infection in respiratory tract epithelia is scarce. Various studies in non-differentiated primary respiratory tract cells or cell ...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2023-05-10 | PXD032673 | Pride
African swine fever is a viral disease of swine caused by the African swine fever virus (ASFV). Currently, ASFV is a serious threat to the global pig industry. A viral strategy to undermine host cell response is to establish a global shutoff of host protein synthesis (virus-induced shutoff, vhs). He...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2023-05-31 | PXD039806 | Pride
African swine fever virus (ASFV) is a lethal animal pathogen which enters its host cells through endocytosis. So far, host factors specifically required for ASFV replication have been barely identified. In this study a genome-wide CRISPR/Cas9 knockout screen in porcine cells indicated that the genes...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2023-08-21 | PXD034242 | Pride
Marek's disease virus (MDV) belongs to the alphaherpesviruses and is the causative agent of fatal T cell lymphomas in chickens. Aftermaths of MDV infections lead to substantial losses in poultry industry and there is evidence that MDV constantly evolves towards higher virulence. This study takes a d...
ORGANISM(S): Gallus gallus 
African swine fever virus (ASFV) is a large DNA virus causing a highly contagious disease in domestic and wild boar, for which no treatment is available. ASFV vaccine development is hindered by large gaps in knowledge considering virus protein function and virus-host interaction. This study shows th...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2023-01-23 | PXD035695 | Pride
Quantitiative analysis of proteomes of porcine macrophages and the stable cell line WSL infected with African swine fever virus using a nanoLC MALDI-Tof/Tof MS platform. The impact of the infection on the two cell types was analyzed using Gene Ontology term and KEGG pathway enrichment analysis.
ORGANISM(S): Sus Scrofa 
The African swine fever virus (ASFV) is a large and complex DNA virus that causes a highly le-thal disease in swine, for which no antiviral drugs or vaccines are currently available. Studying viral–host protein-protein interactions advances our understanding of the molecular mecha-nisms underlying v...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2024-09-17 | PXD054169 | Pride
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