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TranscriptomicsMonopolar attachment of sister kinetochores at meiosis I requires casein kinase 1.
The segregation of maternal centromeres away from the paternal ones during the first division of meiosis depends on the attachment of sister kinetochores to microtubules emanating from the same spindle pole. In budding yeast monopolar attachment requires the recruitment to kinetochores of a protein ...
ORGANISM(S): Saccharomyces cerevisiae 
2010-06-10 | E-GEOD-4792 | biostudies-arrayexpress
TranscriptomicsMurine CD8 T cell gene expression in reponse to type I interferon
To investigate type I interferon regulated genes in CD8+ T cells, we used microarray analyses after stimulation of primary murine T cell cultures. Negatively sorted T cells from naive C57Bl/6 mice were incubated with PBS or anti-CD3 in presence or absence of type I interferon (IFN-4a, 500U/mL). Afte...
ORGANISM(S): Mus musculus 
2014-06-30 | E-GEOD-57421 | biostudies-arrayexpress
MetabolomicsFecal microbiota transplantation plus anti-PD-1 immunotherapy in advanced melanoma: a phase I trial

Fecal microbiota transplantation (FMT) represents a potential strategy to overcome resistance to immune checkpoint inhibitors in patients with refractory melanoma; however, the role of FMT in first-line treatment settings has not been evaluated. We conducted a multicenter phase I trial combining ...

2025-02-27 | MTBLS711 | MetaboLights
ProteomicsStructure of the minimal type I-F2 CRISPR-Cas DNA-interference complex
CRISPR–Cas systems provide adaptive immunity in prokaryotes by targeting and degrading invasive genetic elements. Among them, the type I-F2 system represents the most compact type I CRISPR–Cas system, distinguished by the absence of small and large subunits. These subunits are otherwise essential fo...
ORGANISM(S): Shewanella putrefaciens CN-32 
2026-03-09 | PXD068253 | Pride
Cryo-em Shewanella putrefaciens Hdx-ms Dna interference Interference complex 
MetabolomicsA novel targeted/untargeted GC-Orbitrap metabolomics methodology applied to Candida albicans and Staphylococcus aureus biofilms

INTRODUCTION: Combined infections from Candida albicans and Staphylococcus aureus are a leading cause of death in the developed world. Evidence suggests that Candida enhances the virulence of Staphylococcus - hyphae penetrate through tissue bar...

2017-02-20 | MTBLS370 | MetaboLights
ProteomicsDevelopment and systematic evaluation of decellularization protocols for rat diaphragms
We decellularized rat diaphragms with the main detergents 1% or 0.1% sodium dodecyl sulfate (SDS) and 4% sodium deoxycholate (SDC) by orbital shaking (OS) or retrograde perfusion (RP) through the vena cava. Our systematic comparison entails evaluation of decellularized diaphragmatic samples by (1) q...
ORGANISM(S): Rattus norvegicus (Rat) 
2024-05-07 | PXD042219 | Pride
Decellularized rat diaphragm proteomics 
UnknownGenomic Analysis of Pasteurella atlantica Provides Insight on Its Virulence Factors and Phylogeny and Highlights the Potential of Reverse Vaccinology in Aquaculture.
Not available
S-EPMC8226905 | biostudies-literature
UnknownEstimation of the Controlled Release of Antioxidants from β-Cyclodextrin/Chamomile (Matricaria chamomilla L.) or Milk Thistle (Silybum marianum L.), Asteraceae, Hydrophilic Extract Complexes through the Fast and Cheap Spectrophotometric Technique.
Not available
S-EPMC10303029 | biostudies-literature
ProteomicsProteomic Profiling of Colorectal Liver Metastases Reveals Histopathological Response-Specific Molecular Signatures of Chemotherapy Efficacy
Background: Chemoresistance in treatment of colorectal liver metastases (CRLM) poses a serious challenge in preventing disease relapse, with up to 80% of patients developing drug resistance over the course of treatment. Proteomic signatures of responsive vs. non-responsive metastases can provide in...
ORGANISM(S): Homo sapiens (Human) 
2026-04-13 | PXD065812 | Pride
Human  crlm  crc 
UnknownEB1 and cytoplasmic dynein mediate protrusion dynamics for efficient 3-dimensional cell migration.
Not available
S-EPMC5893312 | biostudies-literature
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