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UnknownSecondary somatic mutations restoring BRCA1/2 predict chemotherapy resistance in hereditary ovarian carcinomas.
Not available
S-EPMC3157963 | biostudies-literature
TranscriptomicsOvarian Tumor Samples: mixed reference of 106 pooled ovarian samples vs. individual patient ovarian sample
The goal of the study was to identify molecular subgroups that might predict clinical outcomes in serous epithelial ovarian cancer (EOC) patients. A second objective was to identify potential therapeutic targets for serous EOC based on improved understanding of the molecular diversity of the diseas...
ORGANISM(S): Homo sapiens 
2013-12-26 | E-GEOD-51088 | biostudies-arrayexpress
UnknownChallenges and Opportunities in Engaging Primary Care Providers in BRCA Testing: Results from the BFOR Study.
Not available
S-EPMC9198181 | biostudies-literature
UnknownBRCA1 and BRCA2 mutation analysis of 208 Ashkenazi Jewish women with ovarian cancer.
Not available
S-EPMC1288193 | biostudies-literature
TranscriptomicsExpression changes following siRNA knockdown of ADRM1 in ovarian cell line OAW42
Knock-down of ovarian cancer amplification target ADRM1 leads to down regulation of GIPC1 and up-regulation of RECK. Among 20q13-amplified genes in ovarian cancer, ADRM1 overexpression was the most highly correlated with amplification, and was significantly upregulated with respect to stage, recurr...
ORGANISM(S): Homo sapiens 
2011-01-14 | E-GEOD-26634 | biostudies-arrayexpress
TranscriptomicsSalivary Transcriptomic and Proteomic Biomarkers for Breast Cancer Detection
A sensitive assay to identify biomarkers that can accurately diagnose the onset of breast cancer using non-invasively collected clinical specimens is ideal for early detection. In this study, we have conducted a prospective sample collection and retrospective blinded validation (PRoBE design) to eva...
ORGANISM(S): Homo sapiens 
2010-02-21 | E-GEOD-20266 | biostudies-arrayexpress
UnknownTargeted BRCA1/2 population screening among Ashkenazi Jewish individuals using a web-enabled medical model: An observational cohort study.
Not available
S-EPMC9306016 | biostudies-literature
UnknownSurvival from breast cancer in women with a BRCA2 mutation by treatment.
Not available
S-EPMC8076275 | biostudies-literature
UnknownInheritance of deleterious mutations at both BRCA1 and BRCA2 in an international sample of 32,295 women.
Not available
S-EPMC5106833 | biostudies-literature
UnknownAssociation of breast cancer risk in BRCA1 and BRCA2 mutation carriers with genetic variants showing differential allelic expression: identification of a modifier of breast cancer risk at locus 11q22.3.
Not available
S-EPMC5222911 | biostudies-literature
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