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MetabolomicsA multi-omics approach to study peroxisome proliferator-activated receptor mediated regulation of lipid metabolism in Atlantic cod (Gadus morhua)
Lipid metabolism is essential in maintaining energy homeostasis in multicellular organisms. In vertebrates, a group of nuclear receptor transcription factors named peroxisome proliferator-activated receptors (PPARs, NR1C) regulate the expression of many genes involved in these processes. We have rec...
2022-02-28 | MTBLS2131 | MetaboLights
TranscriptomicsGenome-wide transcriptional responses to benzo[a]pyrene and clofibrate in the tunicate Oikopleura dioica
Animals have developed extensive mechanisms of response to xenobiotic chemical attacks. Although recent genome surveys have suggested a broad conservation of the chemical defensome across metazoans, global gene expression responses to xenobiotics are not known in most invertebrates. Here, using high...
ORGANISM(S): Oikopleura dioica 
2013-02-05 | E-GEOD-33818 | biostudies-arrayexpress
TranscriptomicsEffects of methylmercury on genome-wide gene expression in the liver of Atlantic cod (Gadus morhua)
Methylmercury (MeHg) is a highly toxic environmental pollutant. To understand the mechanisms of toxicity of the compound and possibly to discover new biomarkers for environmental monitoring, we have conducted toxicogenomics studies. We designed 126k-cod-oligonucleotide arrays and performed genome-wi...
ORGANISM(S): Gadus morhua 
2013-01-22 | E-GEOD-38746 | biostudies-arrayexpress
TranscriptomicsTrained and untrained human skeletal muscle single-nucleus RNA-sequencing from individuals with type 2 diabetes and control
Single-nuclei RNA sequencing (snRNA-seq) data of human muscle cells. The samples are a part of a study investigating the effect of one-legged high-intensity interval training (HIIT) on the nuclear transcriptional response in skeletal muscle. The HIIT was done on one leg on a cycle ergometer, and vas...
ORGANISM(S): Homo sapiens 
2025-04-24 | E-MTAB-15009 | biostudies-arrayexpress
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