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TranscriptomicsHomogeneous monocytes and macrophages from hES cells following coculture-free differentiation in M-CSF and IL-3.
In the present study we aimed at producing homogeneous populations of monocytes and macrophages from human embryonic stem (hES) cells. Human embryonic stem cell lines KCL001, KCL002, and HUES-2 were differentiated into monocytes by coculture-free differentiation with two growth factors using a three...
ORGANISM(S): Homo sapiens 
2010-05-08 | E-GEOD-15791 | biostudies-arrayexpress
UnknownAnnual Hazard Rates of Recurrence for Breast Cancer During 24 Years of Follow-Up: Results From the International Breast Cancer Study Group Trials I to V.
Not available
S-EPMC4933127 | biostudies-literature
TranscriptomicsDNA methylation profiling of healthy elderly individuals with different lifestyle habits
Illumina Infinium EPIC HumanMethylation BeadChip data from saliva DNA samples from a healthy elderly cohort with individuals in the age range 70-95 in Southwest Sweden. The cohort was stratified into study groups based on participants´answers to a questionnaire of different lifestyle factors includi...
ORGANISM(S): Homo sapiens 
2022-07-23 | E-MTAB-11445 | biostudies-arrayexpress
TranscriptomicsGene expression profiling in primary breast cancer distinguishes patients developing local recurrence after breast-conservation surgery, with or without postoperative radiotherapy.
Gene expression profiling of breast tumors for prognosis of local reccurence. Dual channel arrays with a tumor sample in one channel and a common reference in the other channel.
ORGANISM(S): Homo sapiens 
2011-09-02 | E-GEOD-31863 | biostudies-arrayexpress
ProteomicsLC-MS Thermal proteome profiling in Arabidopsis thaliana to study ascorbate interaction
Ascorbate is a major plant metabolite that plays crucial roles in various processes, from reactive oxygen scavenging to epigenetic regulation. However, to what extent and how ascorbate modulates metabolism is largely unknown. To address this, we investigated the consequences of chloroplastic and tot...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2024-08-23 | PXD052756 | Pride
Arabidopsis thaliana Termal proteome profiling Q-exactive hf hybrid quadrupole-orbitrap 
TranscriptomicsClinical implications of gene dosage and gene expression patterns in diploid breast carcinoma (CGH)
Genomic and expression profiling using 38K BAC array-CGH and Illumina HT-12 beadchips were performed on 97 diploid invasive breast tumors to assess the impact of gene dosage on gene expression patterns and the effect of other mechanisms on transcriptional levels. Patient stratification was performed...
ORGANISM(S): Homo sapiens 
2010-06-10 | E-GEOD-20483 | biostudies-arrayexpress
TranscriptomicsIdentification of the chemokine CCL28 as a growth and survival factor for human hematopoietic stem- and progenitor cells
To discover novel growth factors for hematopoietic stem- and progenitor cells (HSPCs), we have assessed cytokine responses of cord blood (CB)-derived CD34+ cells in a high-content growth factor screen. We identify the immunoregulatory chemokine (C-C motif) ligand 28 (CCL28) as a novel growth factor ...
ORGANISM(S): Homo sapiens 
2013-06-03 | E-GEOD-45136 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of human umbilical vein endothelial cells treated with valproic acid
Valproic acid (VPA) is a short-chain fatty acid used in the treatment of epilepsy and also considered to be an epigenetic modifier by functioning as a histone deacetylase (HDAC)-inhibitor. The aim of this study was to search for gene altered by VPA in human endothelial cells. Human umbilical vein en...
ORGANISM(S): Homo sapiens 
2012-03-14 | E-GEOD-23909 | biostudies-arrayexpress
GenomicsA network including TGFβ/Smad4, Gata2 and p57 regulates proliferation of mouse hematopoietic stem/progenitor cells [ChIP-seq]
Transforming growth factor-β (TGFβ) is a potent inhibitor of hematopoietic stem cell (HSC) proliferation. However, the precise mechanism for this effect is unknown. Here, we have identified the transcription factor Gata2, previously described as an important regulator of HSC function, as an early ...
ORGANISM(S): Mus musculus 
2016-09-01 | E-GEOD-73641 | biostudies-arrayexpress
UnknownBacterial contamination and greenhouse gas emissions: A randomised study of reuse versus single-use of infusion-set components for intravenous anaesthesia.
Not available
S-EPMC11556887 | biostudies-literature
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