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ProteomicsEffect of acadesine and overexpression of the karyopherin Kap123 on nuclear abundance of yeast proteins
Based on genetic and affinity chromatography experiments, the karyopherin Kap123 was identified as an important player in the cellular response to the drug acadesine (AICAR, 5′-phosphoribosyl-5-amino-4-imidazole carboxamide). Since Kap123 mediates nuclear import of multiple proteins we hypothesized ...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2018-11-23 | PXD007779 | Pride
Karyopherin Yeast Nucleus Aicar 
UnknownCloning and characterization of human karyopherin beta3.
Not available
S-EPMC20743 | biostudies-literature
UnknownKaryopherin abnormalities in neurodegenerative proteinopathies.
Not available
S-EPMC8194669 | biostudies-literature
UnknownNuclear import by karyopherin-βs: recognition and inhibition.
Not available
S-EPMC3135726 | biostudies-literature
GenomicsDisease-specific alteration of karyopherin-alpha 4 subtype establishes feed-forward oncogenic signaling in squamous cell carcinoma
Disease-specific alteration of karyopherin-alpha 4 subtype establishes feed-forward oncogenic signaling in squamous cell carcinoma
PRJNA529089 | ENA
UnknownRecognition of nuclear targeting signals by Karyopherin-β proteins.
Not available
S-EPMC2994982 | biostudies-literature
UnknownEvolutionary and transcriptional analysis of karyopherin beta superfamily proteins.
Not available
S-EPMC3837465 | biostudies-literature
TranscriptomicsDisease-specific alteration of karyopherin-alpha 4 subtype establishes feed-forward oncogenic signaling in squamous cell carcinoma
Nuclear import, mediated in part by karyopherin-alpha 4 (KPNA) subtypes, regulates transcription factor access to the genome and determines cell fate. However, the cancer-specific changes of KPNA subtypes and the relevancy in cancer biology remain largely unknown. Here, we report that KPNA4, encodin...
ORGANISM(S): Homo sapiens 
2019-12-22 | GSE128853 | GEO
UnknownKaryopherin beta2 mediates nuclear import of a mRNA binding protein.
Not available
S-EPMC24630 | biostudies-literature
UnknownKaryopherin-βs play a key role as a phase separation regulator.
Not available
S-EPMC8457648 | biostudies-literature
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