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ProteomicsChronic high glucose condition reduced expressions of intercellular adhesion molecules and increased intercellular hyperpermeability in periodontal epithelium.
There is a close relationship between hyperglycemia in diabetes and progression of periodontal disease. This study aims to investigate the effect of hyperglycemia on the barrier function of gingival epithelial cells as a cause of hyperglycemia-exacerbated periodontitis in diabetes mellitus. Abnormal...
ORGANISM(S): Mus Musculus (mouse) 
2023-07-29 | PXD035613 | JPOST Repository
ProteomicsPeriodontal pathogen induces entero-hepatic metabolic derangements in type 2 diabetic mouse model
This is the first report of the metabolic and metaproteomic integrated changes in the gut and liver by the swallowed periodontopathogen. Periodontal disease pathogen Porphyromonas gingivalis are observed in faeces as peptides level in proteomic analysis and make changes in bowel microbial compositio...
ORGANISM(S): Cellular Organisms 
2021-09-21 | PXD021851 | JPOST Repository
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