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TranscriptomicsExpression Profile of Chicken Primitive Streak (HH4) Tissues
In birds and mammals, all mesoderm cells are generated from the primitive streak. Nascent mesoderm cells contain unique dorso-ventral (D/V) identities depending on their relative ingression position along the streak. Molecular mechanisms controlling this initial phase of mesoderm diversification are...
ORGANISM(S): Gallus gallus 
2010-07-29 | E-GEOD-22230 | biostudies-arrayexpress
TranscriptomicsGene expression profiles regulated by Tead2 mutants, Yap, and cell density in NIH3T3 cells
Regulation of organ size is important for development and tissue homeostasis. In Drosophila, Hippo signaling controls organ size by regulating the activity of a TEAD transcription factor, Scalloped, through modulation of its coactivator protein Yki. The role of mammalian Tead proteins in growth r...
ORGANISM(S): Mus musculus 
2008-11-20 | E-GEOD-12498 | biostudies-arrayexpress
TranscriptomicsGenome-wide expression analysis of the mouse pars tuberalis (PT) under chronic short-day and long-day conditions
Living organisms detect seasonal changes in day length (photoperiod), and alter their physiological functions accordingly, to fit seasonal environmental changes. This photoperiodic system is implicated in seasonal affective disorders and the season-associated symptoms observed in bipolar disease and...
ORGANISM(S): Mus musculus 
2010-12-02 | E-GEOD-24775 | biostudies-arrayexpress
TranscriptomicsExpression data from human induced pluripotent stem cells derived retinal pigment epithelium (hiPSC-RPE)
We generated hiPSCs from patients fibloblast with retinitis pigmentosa (RP) using retrovirus and Sendai virus vectors, which we differentiated into hiPSC derived retinal pigment epithelium using two different methods (SDIA and SFEB methods). We investigated whether these hiPSC-RPE colonies, which we...
ORGANISM(S): Homo sapiens 
2014-11-03 | E-GEOD-50738 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Coturnix japonica during the photoinduction process.
The molecular mechanism of photoperiodic time measurement remains unknown in animals. Japanese quail is an excellent model for studying these phenomena because of their rapid and dramatic response to photoperiod. When quail are transferred from short to long day conditions, increase in plasma gonado...
ORGANISM(S): Coturnix japonica 
2008-11-06 | E-GEOD-8017 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of chicken and Japanese quail
Since Japanese quail and chicken belong to the same order Galliforms, DNA sequence of both species are highly conserved and proved to be applicable for various analyses each other. Quail are commonly used to address physiological questions for reasons of economy. To test whether chicken microarrays ...
ORGANISM(S): Coturnix japonica 
2008-11-06 | E-GEOD-8016 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of quail MBH under short and long day conditions.
Various physiological processes and behaviours are controlled by changing daylength. To dissect genes involved in the photoperiodic changes in physiology and behaviour, global expression analysis was performed using quail kept under short and long day conditions. Experiment Overall Design: The medio...
ORGANISM(S): Coturnix japonica 
2008-11-06 | E-GEOD-8018 | biostudies-arrayexpress
TranscriptomicsExpression profile of adult mouse 51 CNS regions
The adult mammalian brain is composed of distinct regions that have specialized roles. To dissect molecularly this complex structure, we conducted a project, named the BrainStars (B*) project, in which we sampled ~50 small brain regions, including sensory centers and centers for motion, time, memory...
ORGANISM(S): Mus musculus 
2011-08-11 | E-GEOD-16496 | biostudies-arrayexpress
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