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ProteomicsIMPROVED N- AND O-GLYCOPEPTIDE IDENTIFICATION USING HIGH-FIELD ASYMMETRIC WAVEFORM ION MOBILITY SPECTROMETRY (FAIMS)
Mass spectrometry is the premier tool for identifying and quantifying site-specific protein glycosylation globally. Analysis of intact glycopeptides often requires an enrichment step, after which the samples remain highly complex and exhibit a broad dynamic range of abundance. Here, we evaluated th...
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD038673 | Pride
Faims N-glycopeptides Mass spectrometry O-glycopeptides Glycoproteomics 
ProteomicsStress-induced ribosome degradation in Bacillus subtilis is mediated by the RNase Y-specificity complex
Limiting the synthesis and activity of ribosomes is crucial for responding to various stresses, including nutrient starvation or proteotoxic stress. In Bacillus subtilis, this is achieved through the coordinated action of the alarmones (p)ppGpp and the transcription factor Spx. In this study, we per...
ORGANISM(S): Bacillus subtilis 
2026-04-09 | PXD065465 | Pride
UnknownDifferential expression dynamics of Growth differentiation factor9 (GDF9) and Bone morphogenetic factor15 (BMP15) mRNA transcripts during in vitro maturation of buffalo (Bubalus bubalis) cumulus-oocyte complexes.
Not available
S-EPMC3663994 | biostudies-literature
UnknownCation leak underlies neuronal excitability in an HCN1 developmental and epileptic encephalopathy.
Not available
S-EPMC8370418 | biostudies-literature
ProteomicsTargeting the translation machinery: The RNase Y specificity factor Y-complex coordinates ribosome degradation
Limiting the synthesis and activity of ribosomes is crucial for responding to various stresses, including nutrient starvation or proteotoxic stress. In Bacillus subtilis, this is achieved through the coordinated action of the alarmones (p)ppGpp and the transcription factor Spx. In this study, we per...
ORGANISM(S): Bacillus subtilis 
2026-04-09 | PXD065462 | Pride
Rnase y Ribosome Bacillus subtilis 
ProteomicsStress-induced ribosome degradation in Bacillus subtilis is mediated by the RNase Y-specificity complex
Limiting the synthesis and activity of ribosomes is crucial for adaptation to stresses, such as heat or nutrient starvation. In Bacillus subtilis, this can be achieved through the coordinated action of the alarmones (p)ppGpp and the transcription factor Spx. Here, we performed a genetic screen to un...
ORGANISM(S): Bacillus sp. B-23280 
2026-04-09 | PXD074523 | Pride
ProteomicsA non-canonical type III toxin–antitoxin system encoded in Streptococcus pyogenes prophage promotes phage resistance
Toxin-antitoxin systems are widespread in bacteria. These systems typically consist of two components: a toxin that disrupts essential cellular processes and a cognate antitoxin that neutralizes its activity. However, their experimental characterization, particularly in the human pathogen Streptococ...
ORGANISM(S): Streptococcus pyogenes M1 GAS 
2026-09-23 | PXD084627 | Pride
Streptococcus pyogenes Toxin–antitoxin 
UnknownSi doped T6 carbon structure as an anode material for Li-ion batteries: An ab initio study.
Not available
S-EPMC5124951 | biostudies-literature
ProteomicsA platform for the recombinant production of Group A Streptococcus glycoconjugate vaccines
Strep A are human-exclusive bacterial pathogens killing annually more than 500,000 patients, and no current licensed vaccine exists. Strep A bacteria are highly diverse, but all produce an essential, abundant, and conserved main surface carbohydrate, the Group A Carbohydrate (GAC). GAC contains a rh...
ORGANISM(S): Streptococcus pyogenes serotype M1 
2025-04-22 | PXD037039 | Pride
Glycoconjugate Streptococcus Glycoproteomics 
TranscriptomicsDEFINING A RAT BLOOD PRESSURE QUANTITATIVE TRAIT LOCUS TO A <81.8KB CONGENIC SEGMENT: COMPREHENSIVE SEQUENCING AND RENAL TRANSCRIPTOME ANALYSIS.
Evidence from multiple linkage and genome-wide association studies suggest that human chromosome 2 (HSA2) contains alleles that influence blood pressure (BP). Homologous to a large segment of HSA2 is rat chromosome 9 (RNO9), to which a BP quantitative trait locus (QTL) was previously mapped. The obj...
ORGANISM(S): Rattus norvegicus 
2010-07-15 | E-GEOD-22515 | biostudies-arrayexpress
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