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ProteomicsProteomics reveals the essential role for LPXN in human iTreg suppression
Regulatory T cells are critical in the modulation of immune responses. Accordingly, the manipulation and implementation of in vitro induced Treg cells to control immune function has a significant potential in clinical medicine. However, the use of iTregs as therapeutics is complicated by their poor ...
ORGANISM(S): Homo Sapiens 
2026-08-27 | PXD052690 | panorama
TranscriptomicsscRNA-seq of brain and spinal cord of mice where Cip2a locus has been disrupted and wild-type control mice at the peak of Experimental Autoimmune Encephalomyelis
We induced Experimental Autoimmune Encephalomyelis (EAE) in mice carrying a gene-trap disruption of Cip2a (hereafter referred to as knockout [KO] mice) and wild-type (WT) control C57BL/6J male and female mice, aged 8-12 weeks. We performed scRNA-seq analysis of central nervous system (CNS), i.e., br...
ORGANISM(S): Mus musculus 
2026-10-15 | E-MTAB-17720 | biostudies-arrayexpress
TranscriptomicsscRNA-seq of lymph node of mice where Cip2a locus has been disrupted and wild-type control mice at the peak of Experimental Autoimmune Encephalomyelis
We induced EAE in mice carrying a gene-trap disruption of Cip2a (hereafter referred to as knockout [KO] mice) and wild-type (WT) control C57BL/6J male and female mice, aged 8-12 weeks. We performed scRNA-seq analysis of lymph node cells from five WT and five KO mice at the peak of EAE. The goal was ...
ORGANISM(S): Mus musculus 
2026-09-30 | E-MTAB-17644 | biostudies-arrayexpress
TranscriptomicsRRBS (DNA methylation) analysis of CD4+ CD8+ and CD4-CD8- fractions of PBMC cells collected from 7 case children, who were positive for type 1 diabetes specific autoantibodies, and their matched controls, sampled at 3, 6, 12, 18, 24, and 36 months of age
10.1007/s00125-022-05657-x
ORGANISM(S): Homo sapiens 
2022-02-14 | E-MTAB-11088 | biostudies-arrayexpress
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