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ProteomicsTripartite interactions of PKA catalytic subunit and C-terminal domains of cardiac Ca2+ channel may modulate its β-adrenergic regulation
The β-adrenergic augmentation of cardiac contraction, by increasing the conductivity of L-type voltage-gated CaV1.2 channels, is of great physiological and pathophysiological importance. Stimulation of β-adrenergic receptors (βAR) activates protein kinase A (PKA) through separation of regulatory (PK...
ORGANISM(S): Homo sapiens (Human) 
2024-11-22 | PXD057841 | Pride
Calcium channel  protein‐protein interaction  adrenergic regulation  cardiac  protein kinase a (pka)  heterologous expression 
MetabolomicsExtreme genome diversity and cryptic speciation in a harmful algal bloom forming eukaryote

Harmful algal blooms (HABs) of the toxic haptophyte Prymnesium parvum are a recurrent problem in many inland and estuarine waters around the world. Strains of P. parvum vary in the toxins they produce and in other physiological traits associated with HABs, but the genetic basis ...

2023-04-26 | MTBLS5893 | MetaboLights
UnknownA Selective and Cell-Permeable Mitochondrial Calcium Uniporter (MCU) Inhibitor Preserves Mitochondrial Bioenergetics after Hypoxia/Reoxygenation Injury.
Not available
S-EPMC6346394 | biostudies-literature
UnknownThe rationale, design, and baseline characteristics of the Women's Health Initiative Memory Study of Younger Women (WHIMS-Y).
Not available
S-EPMC3684042 | biostudies-literature
UnknownEffect of Antimicrobial Therapy on Respiratory Hospitalization or Death in Adults With Idiopathic Pulmonary Fibrosis: The CleanUP-IPF Randomized Clinical Trial.
Not available
S-EPMC8114133 | biostudies-literature
UnknownPathogenic variants for Mendelian and complex traits in exomes of 6,517 European and African Americans: implications for the return of incidental results.
Not available
S-EPMC4129409 | biostudies-literature
UnknownThe genetic landscape of Lynch syndrome in the Israeli population.
Not available
S-EPMC11567984 | biostudies-literature
UnknownLongitudinal Correlates of Health Risk Behaviors in Children and Adolescents with Type 2 Diabetes.
Not available
S-EPMC4414713 | biostudies-literature
UnknownExome sequencing of extreme phenotypes identifies DCTN4 as a modifier of chronic Pseudomonas aeruginosa infection in cystic fibrosis.
Not available
S-EPMC3702264 | biostudies-literature
UnknownEffect of clopidogrel on early failure of arteriovenous fistulas for hemodialysis: a randomized controlled trial.
Not available
S-EPMC4943222 | biostudies-literature
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