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TranscriptomicsNO001: Kdm5c controls promoter and enhancer activities
The functional organization of eukaryotic genomes correlates with specific patterns of histone methylations. Regulatory regions in genomes like enhancers and promoters differ in their extent of methylation of histone H3 at lysine-4 (H3K4), but it is largely unknown how the different methylation stat...
ORGANISM(S): Mus musculus 
2013-04-05 | E-GEOD-38862 | biostudies-arrayexpress
TranscriptomicsComparative transcriptional profiling of the lung discriminates S. pneumoniae and Influenza A Virus infections
Peumonia is the most common cause of death due to infectious diseases in the western hemisphere. The molecular events associated with pulmonary infections caused by Streptococcus pneumoniae and Influenza A virus are incompletely understood. Pathophysiological and protective processes are initiated b...
ORGANISM(S): Mus musculus 
2010-07-01 | E-GEOD-5289 | biostudies-arrayexpress
TranscriptomicsNO001: Kdm5c controls promoter and enhancer activities
RNA from four independent cultures from each sh Kdm5c #1, sh Kdm5c #2 and non-targeting shRNA polyclonal cell lines were hybridized in dye-swap against a common reference of RNA from IB10 ES cells
ORGANISM(S): Mus musculus 
2013-04-05 | E-MTAB-1177 | biostudies-arrayexpress
UnknownConcise gene signature for point-of-care classification of tuberculosis.
Not available
S-EPMC4734838 | biostudies-literature
UnknownDeletion of nuoG from the Vaccine Candidate Mycobacterium bovis BCG ΔureC::hly Improves Protection against Tuberculosis.
Not available
S-EPMC4895111 | biostudies-literature
TranscriptomicsSubunit-specific vs. non-selective proteasome modulation in limiting inflammation in experimental colitis
Inflammatory bowel disease (IBD), comprising CrohnM-BM-4s disease and Ulcerative colitis, is characterized by chronic relapsing inflammation of the gut. It has been shown that increased proteasomal activity is associated with the expression of immunoproteasomes, which enhances NF-kB activation and t...
ORGANISM(S): Mus musculus 
2010-07-06 | E-GEOD-18163 | biostudies-arrayexpress
TranscriptomicsTB disease classification
Validation of gene expression levels to assess classification of TB patients and healthy controls qPCR gene expression profiling. Whole blood gene expression from TB patients (positive in GenXpert assay) and healthy controls; both tuberculin skin test positive (TSTpos) and -negative (TSTneg).
ORGANISM(S): Homo sapiens 
2015-12-21 | E-GEOD-74092 | biostudies-arrayexpress
UnknownMachine-learning aided in situ drug sensitivity screening predicts treatment outcomes in ovarian PDX tumors.
Not available
S-EPMC9136609 | biostudies-literature
TranscriptomicsGene expression of murine B cells activated via TLR4 or TLR4 + CD40: Group1 naM-CM-/ve B cells, Group2 LPS activated B cells 24h, Group3 LPS + anti-CD40 activated B cells 24h, Group4 LPS activated B cells 72h, and Group5 LPS + anti-CD40 activated B cells 72h.
Murine B cells can be activated via the surface receptors TLR4 and CD40. For a global assessment of differences in gene expression between these two different modes of B cell activation a genome wide transcriptome analysis was performed. In order to dissect different gene expression profiles of B ce...
ORGANISM(S): Mus musculus 
2014-02-24 | E-GEOD-35998 | biostudies-arrayexpress
UnknowncGAS facilitates sensing of extracellular cyclic dinucleotides to activate innate immunity.
Not available
S-EPMC6446192 | biostudies-literature
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