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TranscriptomicsAn ultrasensitive mechanism regulates influenza virus-induced inflammation
Whole-genome, time-course data was developed from the lungs of influenza infected mice to better characterize the dynamics of the host immune response during infection. Lung for microarray studies were obtained from female, five-week old C57BL/6Js infected with influenza viruses. Forty-two animals ...
ORGANISM(S): Mus musculus 
2015-06-12 | E-GEOD-63786 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of M. mulatta (Rhesus macaques) infected with H1N1 and pH1N1 influenza
Annually, influenza A viruses circulate the world causing wide-spread sickness, economic loss, and death. One way to better defend against influenza virus-induced disease may be to develop novel host-based therapies, targeted at mitigating viral pathogenesis through the management of virus-dysregula...
ORGANISM(S): Macaca mulatta 
2012-10-01 | E-GEOD-39018 | biostudies-arrayexpress
TranscriptomicsComparison of gene expression in thyrocytes between wildtype and thyroid-specific IFNg transgenic mice
Hürthle cells are found in thyroid tumors and autoimmunity, and have a unique appearance characterized by swollen eosinophilic cytoplasm filled with mitochondria and hyperchromatic nucleus. The pathogenesis of Hürthle cells remains unknown. We have generated transgenic mice expressing IFNg specifica...
ORGANISM(S): Mus musculus 
2009-07-01 | E-GEOD-15114 | biostudies-arrayexpress
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