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MetabolomicsThe enduring effects of early-life HFHS exposure and microbiota-targeted interventions on blood metabolome in adult female and male mice

Blood metabolomics of 12-week-old female and male C57BL/6J mice that were exposed to either a control or an unhealthy high-fat/high-sugar (HFHS) diet during early-life, or early-life HFHS diet supplemented with a microbiota-targeted intervention (either a prebiotic combination (fructo-oligosaccha...

2026-01-27 | MTBLS12714 | MetaboLights
ProteomicsGonatopoulos-Pournatzis _eIF4Gmicroexon_P105_Lumos
A This dataset consists of 24 raw MS files, acquired on Orbitrap Fusion Lumos Tribrid mass spectrometer operated in Data Dependent Acquisition mode. B Mouse samples were generated by Thomas Gonatopoulos-Pournatzis. Proteomics sample preparation and mass spectrometric acquisition was performed by Sh...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2019-12-04 | MSV000084658 | MassIVE
ProteomicsPeptidomic analysis of pancreatic neurodendocrine tumours (Glucagonoma)
A peptidomic analysis of plasma from patients with well characterised pancreatic neuroendocrine tumours (PNET) was performed. A nano LC-MS analysis identified a number of peptides from the glucagon gene, which were idenfiried in a previous case study using multiple immunoassays. Peptides to other pr...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-08-31 | MSV000082880 | MassIVE
ProteomicsProteomic and Phosphoproteomic Signatures of Disease Progression in Unmutated IGHV Chronic Lymphocytic Leukemia
Chronic lymphocytic leukemia (CLL) patients with an unmutated (UM) immunoglobulin heavy chain variable region gene (IGHV) typically have poorer prognosis and require earlier treatment compared to those with mutated IGHV. Nevertheless, disease progression among UM-CLL patients is heterogeneous, with ...
ORGANISM(S): Homo sapiens (Human) 
2026-09-07 | PXD072006 | Pride
Phosphoproteomics Chronic lymphocytic leukemia Disease progression Unmutated ighv Proteomics 
TranscriptomicsExpression data from mouse skin scar after wounding
Using a TCF reporter mouse which contain a LacZ gene downstream of a c-fos minimal promoter and three consensus TCF-binding motifs, we wounded skin and harvested the scar tissue one week post wounding. Healing tissue sorted to group of cells : β-Gal+ cells (R) expression data with β-Gal- cells (L)...
ORGANISM(S): Mus musculus 
2011-07-25 | E-GEOD-30913 | biostudies-arrayexpress
ProteomicsA Structural Mechanism for Noncanonical GPCR Signal Transduction in the Hedgehog Pathway
The Hedgehog (Hh) signaling pathway is fundamental to embryogenesis, tissue homeostasis, and cancer. Hh signals are transduced via an unusual mechanism: upon agonist-induced phosphorylation, the noncanonical G protein-coupled receptor SMOOTHENED (SMO) binds the catalytic subunit of protein kinase A ...
ORGANISM(S): Mus musculus (Mouse) 
2026-03-26 | PXD067578 | Pride
Smoothened Protein kinase a Hedgehog 
UnknownLeveraging the Expertise of the CTSA Program to Increase the Impact and Efficiency of Clinical Trials.
Not available
S-EPMC10773966 | biostudies-literature
UnknownIs adjuvant chemotherapy of benefit for postmenopausal women who receive endocrine treatment for highly endocrine-responsive, node-positive breast cancer? International Breast Cancer Study Group Trials VII and 12-93.
Not available
S-EPMC3589110 | biostudies-literature
UnknownA Type 1 Diabetes Genetic Risk Score Predicts Progression of Islet Autoimmunity and Development of Type 1 Diabetes in Individuals at Risk.
Not available
S-EPMC6105323 | biostudies-literature
UnknownClopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA.
Not available
S-EPMC6193486 | biostudies-literature
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