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TranscriptomicsGene expression from Inducible TOC1 expression in Arabidopsis seedlings
The first described feedback loop of the Arabidopsis circadian clock is based on reciprocal regulation between TOC1 and CCA1/LHY. CCA1 and LHY are MYB transcription factors that bind directly to the TOC1 promoter to negatively regulate its expression. Conversely, the activity of TOC1 has remained le...
ORGANISM(S): Arabidopsis thaliana 
2012-01-15 | E-GEOD-34897 | biostudies-arrayexpress
TranscriptomicsCircadian temporal profiling of MMH-D3 hepatocytes
The circadian clock generates daily rhythms in mammalian liver processes, such as glucose and lipid homeostasis, xenobiotic metabolism, and regeneration. The mechanisms governing these rhythms are not well understood, particularly the distinct contributions of the cell-autonomous clock and central p...
ORGANISM(S): Mus musculus 
2011-11-03 | E-GEOD-31049 | biostudies-arrayexpress
TranscriptomicsKidney Transplant Rejection and Tissue Injury by Gene Profiling of Biopsies and Peripheral Blood Lymphocytes
We used DNA microarrays (HG-U95Av2 GeneChips) to determine gene expression profiles for kidney biopsies and peripheral blood lymphocytes (PBLs) in transplant patients. Sample classes include kidney biopsies and PBLs from patients with 1) healthy normal donor kidneys, 2) well-functioning transplants ...
ORGANISM(S): Homo sapiens 
2004-07-14 | E-GEOD-1563 | biostudies-arrayexpress
ProteomicsCryoEM Structures of Arabidopsis DDR Complexes Involved in RNA-directed DNA Methylation
Chemical cross-linking coupled to mass spectrometry was used to study the A. thaliana DDR complex consisting of DMS3, RMD1 and a peptide from the interaction region of DRD1. Cross-linking was performed using different cross-linking chemistries: disuccinimidyl suberate (DSS) and a combination of adip...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2019-07-15 | PXD013470 | Pride
Chemical cross-linking  dss  adh  dmtmm  structural proteomics  ddr complex 
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