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ProteomicsKChIP3 promotes Alzheimer´s disease by impairing long-term potentiation and memory
Alzheimer's disease (AD) is a multifactorial disorder with serious social, health, and economic implications, affecting over 30 million individuals worldwide, and this number may triple by the year 2050. To date, there are no accurate biomarkers for early diagnosis nor effective treatments to delay ...
ORGANISM(S): Mus musculus (Mouse) 
2025-06-30 | PXD054699 | Pride
Neuroinflammation Kchip3 Alzheimer´s disease 
GenomicsKChIP3 promotes Alzheimer's disease by impairing long-term potentiation and memory
KChIP3 promotes Alzheimer's disease by impairing long-term potentiation and memory
PRJNA1150916 | ENA
TranscriptomicsKChIP3 promotes Alzheimer's disease by impairing long-term potentiation and memory
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by β -amyloid (βA) peptide accumulation, neuroinflammation, increased synaptic pruning, and cognitive decline. Effective treatments for AD are still lacking. This study investigates the role of potassium channel inter...
ORGANISM(S): Mus musculus 
2025-06-25 | GSE275435 | GEO
UnknownModulation of Kv4.2/KChIP3 interaction by the ceroid lipofuscinosis neuronal 3 protein CLN3.
Not available
S-EPMC7443505 | biostudies-literature
UnknownModulation of the voltage-gated potassium channel (Kv4.3) and the auxiliary protein (KChIP3) interactions by the current activator NS5806.
Not available
S-EPMC4231695 | biostudies-literature
UnknownKChIP3 coupled to Ca2+ oscillations exerts a tonic brake on baseline mucin release in the colon.
Not available
S-EPMC6167051 | biostudies-literature
UnknownSpecific effects of KChIP3/calsenilin/DREAM, but not KChIPs 1, 2 and 4, on calcium signalling and regulated secretion in PC12 cells.
Not available
S-EPMC2474559 | biostudies-literature
GenomicsThe DREAM complex promotes gene body deposition of H2A.Z for target repression
As part of a study of the function of the C. elegans DREAM complex, here we have used ChIP-seq to analyze the patterns of histone variant HTZ-1/H2A.Z and various histone modifications in lin-35(n745) mutants. In addition, we have used RNA-seq to analyze gene expression in lin-35 and htz-1 mutants as...
ORGANISM(S): Caenorhabditis elegans 
2015-04-02 | E-GEOD-62833 | biostudies-arrayexpress
GenomicsArchitecture of Epigenetic Reprogramming Following Twist1 Mediated Epithelial-Mesenchymal Transition [DREAM-seq]
Purpose: to characterize epigenetic changes following Twist1 mediated Epithelial-Mesenchymal Transition in human Methods: we characterized the epigenetic and transcriptome landscapes using whole genome transcriptome analysis by RNA-seq, DNA methylation by digital restriction enzyme analysis of meth...
ORGANISM(S): Homo sapiens 
2013-12-10 | E-GEOD-53025 | biostudies-arrayexpress
UnknownCellular and Subcellular Localisation of Kv4-Associated KChIP Proteins in the Rat Cerebellum.
Not available
S-EPMC7503578 | biostudies-literature
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