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ProteomicsKCNK3 channel dysregulation in PAH
Introduction. Pulmonary arterial hypertension (PAH) is a severe cardiopulmonary disease that may be triggered by exposure to drugs such as dasatinib or facilitated by genetic predispositions. The incidence of dasatinib-associated PAH is estimated at 0.45%, suggesting individual predispositions. The ...
ORGANISM(S): Homo sapiens (Human) 
2025-10-17 | PXD042425 | Pride
Apex Channel dysregulation Turboid Kcnk3 
TranscriptomicsAdrenal gene expression profiles of male and female Kcnk3 null mice in basal conditions or after hormonal treatment.
Primary aldosteronism (PA) is a common form of endocrine hypertension suspected in the presence of arterial hypertension (HT), hypokalemia and low plasma renin levels. While for a long time the genetic causes of PA have remained mysterious, recent findings have revealed an important role for an alte...
ORGANISM(S): Mus musculus 
2012-08-20 | E-GEOD-37825 | biostudies-arrayexpress
TranscriptomicsEffect of KCNK3 mutations on hypoxic mice lungs studied by RNASeq
We sequenced RNA from lungs of mice, subjected to hypoxia, with or without KCNK3 knockout mutations
ORGANISM(S): Mus musculus 
2019-02-18 | GSE84454 | GEO
UnknownKCNK3 Variants Are Associated With Hyperaldosteronism and Hypertension.
Not available
S-EPMC4945430 | biostudies-literature
TranscriptomicsAdrenal gene expression profiles of male and female Kcnk3 null mice in basal conditions or after hormonal treatment.
Primary aldosteronism (PA) is a common form of endocrine hypertension suspected in the presence of arterial hypertension (HT), hypokalemia and low plasma renin levels. While for a long time the genetic causes of PA have remained mysterious, recent findings have revealed an important role for an alte...
ORGANISM(S): Mus musculus 
2012-08-20 | GSE37825 | GEO
GenomicsSus scrofa
RNA-seq data of KCNK3-KO cell (PRJCA044501)
PRJDB39121 | ENA
UnknownProteomic Analysis of KCNK3 Loss of Expression Identified Dysregulated Pathways in Pulmonary Vascular Cells.
Not available
S-EPMC7582549 | biostudies-literature
UnknownCrosstalk between BMP signaling and KCNK3 in phenotypic switching of pulmonary vascular smooth muscle cells.
Not available
S-EPMC9712703 | biostudies-literature
UnknownKCNK3 inhibits proliferation and glucose metabolism of lung adenocarcinoma via activation of AMPK-TXNIP pathway.
Not available
S-EPMC9376064 | biostudies-literature
UnknownThe Impact of Heterozygous KCNK3 Mutations Associated With Pulmonary Arterial Hypertension on Channel Function and Pharmacological Recovery.
Not available
S-EPMC5634293 | biostudies-literature
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