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UnknownZap-Pano: a Photocaged Prodrug of the KDAC Inhibitor Panobinostat.
Not available
S-EPMC9291796 | biostudies-literature
UnknownRapid and transient oxygen consumption increase following acute HDAC/KDAC inhibition in Drosophila tissue.
Not available
S-EPMC5843646 | biostudies-literature
ProteomicsEffects of lysine deacetylase inhibitor treatment on LPS responses of alveolar-like macrophages
Macrophages are key immune cells in tissues that are able to adapt their metabolic phenotype in response to different stimuli. Lysine deacetylases are important enzymes for regulating inflammatory gene expression and their inhibitors have anti-inflammatory effects in models of chronic obstructive pu...
ORGANISM(S): Mus musculus (Mouse) 
2024-02-21 | PXD040933 | Pride
Dia proteomics Alveolar-like macrophages Lps activation Kdac inhibition Mouse 
UnknownLysine deacetylase inhibition promotes relaxation of arterial tone and C-terminal acetylation of HSPB6 (Hsp20) in vascular smooth muscle cells.
Not available
S-EPMC3871448 | biostudies-literature
UnknownDevelopment of novel benzamide class I selective lysine deacetylase inhibitors as potent anticancer agents.
Not available
S-EPMC12217109 | biostudies-literature
ProteomicsUnraveling Lysine Deacetylase Inhibitor Specificities for Endogenous Acetylation Sites
Lysine deacetylases (KDACs) are important regulators of biological processes. KDAC inhibitors (KDACIs) are important tools for basic research and attractive therapeutic candidates, yet their effects on in-vivo acetylation sites are poorly known. Here we obtained acetylation signatures for 19 differe...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2015-02-16 | PXD001377 | Pride
Proteomics Bufexamac Mass spectrometry Silac Nicotinamide Hdac Acetylation Tenovin-6 Kdac Sirtuin Deacetylase inhibitor 
UnknownQuantitative Proteomic Approach Reveals Altered Metabolic Pathways in Response to the Inhibition of Lysine Deacetylases in A549 Cells under Normoxia and Hypoxia.
Not available
S-EPMC8036653 | biostudies-literature
UnknownClass I lysine deacetylases promote glucocorticoid-induced transcriptional repression through functional interaction with LSD1.
Not available
S-EPMC5444329 | biostudies-literature
UnknownLysine deacetylase inhibitors have low selectivity in cells and exhibit predominantly off-target effects.
Not available
S-EPMC11705486 | biostudies-literature
UnknownAugmented Global Protein Acetylation Diminishes Cell Growth and Migration of Cholangiocarcinoma Cells.
Not available
S-EPMC11432552 | biostudies-literature
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