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GenomicsSox10 Binding Analysis in the Central and Peripheral Nervous System
ChIP-seq of Sox10 in spinal cord and sciatic nerve 2 independent Sox10 ChIP samples each for spinal cord (CNS) and sciatic nerve (PNS), with respective inputs
ORGANISM(S): Rattus norvegicus 
2015-04-01 | E-GEOD-64703 | biostudies-arrayexpress
TranscriptomicsTransient Genotype-by-Environment Interactions in the Yeast Genomic Expression Response to Heat Shock
Microarray time courses followed the response of 5 yeast strains to heat shock. Expression variation due to genetic, environmental, and genotype-by-environment interactions were identified. Keywords: Timecourse and single timepoint expression studies of stress response in yeast The genomic express...
ORGANISM(S): Saccharomyces cerevisiae 
2010-05-18 | E-GEOD-15147 | biostudies-arrayexpress
TranscriptomicsRho directs widespread termination of intragenic and stable RNA transcription
The transcription termination factor Rho is a global regulator of RNA polymerase (RNAP). Although individual Rho-dependent terminators have been studied extensively, less is known about the sites of RNAP regulation by Rho on a genome-wide scale. Using chromatin immunoprecipitation and microarrays (...
ORGANISM(S): Escherichia coli 
2010-05-18 | E-GEOD-16562 | biostudies-arrayexpress
GenomicsGenome-wide analysis of EGR2/SOX10 binding in myelinating peripheral nerve
We provide ChIP-Seq analysis of Egr2 and Sox10 transcription factor binding in Schwann cells of rat peripheral nerve ChIP-Seq analysis of Egr2 and Sox10 binding in P15 rat sciatic nerve. Wiggle files of negative log of posterior probability determined by Mosaics.
ORGANISM(S): Rattus norvegicus 
2012-04-01 | E-GEOD-35132 | biostudies-arrayexpress
GenomicsGenetic Framework for GATA Factor Function in Vascular Biology
Vascular endothelial dysfunction underlies the genesis and progression of numerous diseases. Whereas the GATA transcription factor GATA-2 is expressed in endothelial cells and is implicated in coronary heart disease, it has been studied predominantly as a master regulator of hematopoiesis. As many q...
ORGANISM(S): Homo sapiens 
2011-08-11 | E-GEOD-29531 | biostudies-arrayexpress
TranscriptomicsExpression data of sleeping, waking, and sleep deprived in adult heterozygous Cnp M-bM-^@M-^S eGFP-L10a mice
Transcriptomic studies revealed that hundreds of mRNAs show differential expression in the brains of sleeping versus awake rats, mice, flies, and sparrows. Although these results have offered clues regarding the molecular consequences of sleep and sleep loss, their functional significance thus far h...
ORGANISM(S): Mus musculus 
2013-08-20 | E-GEOD-48369 | biostudies-arrayexpress
GenomicsGenome-wide maps of GATA factor occupancy in K562 cells
GATA factors interact with simple DNA motifs (WGATAR) to regulate critical processes, including hematopoiesis, but very few WGATAR motifs are occupied in genomes. Given the rudimentary knowledge of mechanisms underlying this restriction, and how GATA factors establish genetic networks, we used ChIP-...
ORGANISM(S): Homo sapiens 
2009-11-25 | E-GEOD-18868 | biostudies-arrayexpress
GenomicsChIP-seq analysis of SREB during yeast phase growth of Blastomyces dermatitidis at 37oC
ChIP-seq analysis was used to identify B. dermatitidis genes bound by the GATA transcription factor encoded by SREB during growth as yeast at 37oC SREB was engineered to contain an in-frame 3x-hemagglutinin (HA) epitope tag at the C-terminus. The SREB-3xHA construct was under control of its native p...
ORGANISM(S): Blastomyces dermatitidis ATCC 26199 
2015-07-01 | E-GEOD-68680 | biostudies-arrayexpress
GenomicsAutophagy driven by a master regulator of hematopoiesis
Developmental and homeostatic remodeling of cellular organelles is mediated by a complex process termed autophagy. The cohort of proteins that constitute the autophagy machinery function in a multistep biochemical pathway. Though components of the autophagy machinery are broadly expressed, autophagy...
ORGANISM(S): Homo sapiens 
2011-09-30 | E-GEOD-32491 | biostudies-arrayexpress
TranscriptomicsExpression analysis of Escherichia coli MG1655 K-12 WT and M-bM-^HM-^Ffnr mutant
Investigation of whole genome gene expression level changes in a Escherichia coli MG1655 K-12 ?fnr mutant, compared to the wild-type strain. The mutations engineered into this strain produce a strain lacking the FNR protein. WT strains were grown under aerobic and anaerobic growth conditions. A six ...
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 
2013-06-20 | E-GEOD-41189 | biostudies-arrayexpress
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