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TranscriptomicsAdenosine-to-inosine RNA editing controls cathepsin S expression in atherosclerosis by enabling HuR-mediated post-transcriptional regulation
Adenosine-to-inosine (A-to-I) RNA editing, which is catalyzed by a family of adenosine deaminase acting on RNA (ADAR) enzymes, is important in the epitranscriptomic regulation of RNA metabolism. However, the role of A-to-I RNA editing in vascular disease is unknown. Here we show that cathepsin S mRN...
ORGANISM(S): Homo sapiens 
2016-09-05 | E-GEOD-60217 | biostudies-arrayexpress
ProteomicsChemBioID - An integrated chemical biology workflow for the investigation of proximity-induced pharmacology
Modulation of protein-protein interactions with small molecules represents an emerging area of interest in drug discovery. Here we probe the effects of catalytic inhibition on the proximity of CAMKK2. The experiment was supervised by Sabrina Keller and Viviane Reber. This project is part of the IMI ...
ORGANISM(S): Homo sapiens (Human) 
2025-04-30 | PXD058412 | Pride
Bioid 
ProteomicsChemBioID - An integrated chemical biology workflow for the investigation of proximity-induced pharmacology
Modulation of protein-protein interactions with small molecules represents an emerging area of interest in drug discovery. Here we probe the effects of catalytic inhibition on the proximity of CAMKK2. The experiment was supervised by Sabrina Keller and Viviane Reber. This project is part of the IMI ...
ORGANISM(S): Homo sapiens (Human) 
2025-04-30 | PXD058418 | Pride
Bioid 
ProteomicsChemBioID - An integrated chemical biology workflow for the investigation of proximity-induced pharmacology
Modulation of protein-protein interactions with small molecules represents an emerging area of interest in drug discovery. Here we probe the effects of catalytic inhibition of CAMKK2 on the proximity of PRKAA1. The experiment was supervised by Sabrina Keller and Viviane Reber. This project is part o...
ORGANISM(S): Homo sapiens (Human) 
2025-04-30 | PXD058471 | Pride
Bioid 
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