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ProteomicsOxygen-dependent changes in protein expression in Campylobacter jejuni NCTC11168
Using strain NCTC 11168 in carbon (serine)-limited continuous cultures we report the first detailed examination of oxygen-dependent changes in gene and protein expression in Campylobacter jejuni under conditions where the growth rate is fixed. We show that in steady-states established at μ = 0.2 h-1...
ORGANISM(S): Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819 
2017-10-04 | PXD006467 | Pride
Oxygen Electron transport Mass spectrometry Oxidative stress Label-free Campylobacter 
TranscriptomicsRNA-seq analysis of differential gene expression in muscle from Holstein Friesian bulls undergoing diet restriction and compensatory growth
The objective of this study was to examine changes in muscle gene expression of growing bulls during a period of dietary energy restriction followed by a period of subsequent realimentation and compensatory growth. Purebred Holstein Friesian bulls (n=20) were assigned to one of two feeding treatment...
ORGANISM(S): Bos taurus 
2015-09-04 | E-GEOD-64289 | biostudies-arrayexpress
ProteomicsPhosphoprotein dynamics of interacting tumor and T cells by HySic
Functional interactions between cytotoxic T cells and tumor cells are central to anti-cancer immunity. Some of the proteins involved, particularly immune checkpoints expressed by T cells, serve as promising clinical targets in immunotherapy. However, our understanding of the complexity and dynamics ...
ORGANISM(S): Homo sapiens (Human) 
2023-12-20 | PXD046734 | Pride
Cell signaling Phosphoproteomics Interacting cells Co-culture Hysic Human Cancer Silac Cell culture T cells Intercellular communication 
TranscriptomicsCharacterisation of the whole blood mRNA transcriptome in Holstein-Friesian and Jersey calves in response to gradual weaning
The objectives of the study were to use RNA-Seq to examine the effect of (i) breed and (ii) gradual weaning, on the whole blood mRNA transcriptome of artificially reared Holstein-Friesian and Jersey calves. The calves were gradually weaned over 14 days (day (d) -13 to d 0) and mRNA transcription was...
ORGANISM(S): Bos taurus 
2016-08-19 | E-GEOD-76841 | biostudies-arrayexpress
ProteomicsProteomic profiling of anterior pituitary of heifer calves offered either a high or moderate plane of nutrition in early life
Enhanced nutrition during the early calfhood period has been shown to hasten the onset of puberty in heifer calves. The hypothalamic-pituitary-ovarian biochemical signalling axis regulates reproductive development in heifers, with the dynamics of gonadotropin pulsatility within the anterior pituitar...
ORGANISM(S): Bos taurus (Bovine) 
2024-07-04 | PXD042011 | Pride
Anterior pituitary Diet Heifer calves 
UnknownThe centrosomin CM2 domain is a multi-functional binding domain with distinct cell cycle roles.
Not available
S-EPMC5760045 | biostudies-literature
ProteomicsDifferential solubilization and top-down proteomics with FAIMS control experiments applied to mouse brain
5-35 mg brain tissue plugs from mouse left or right hemisphere were homogenized on ice with a pellet pestle homogenizer in a 1.5 mL LoBind Eppendorf tube after addition of 8 uL hexafluoroisopropanol (HFIP) / mg tissue. Once tissue was fully disrupted, an equivolume amount of homogenization buffer (H...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2023-12-25 | MSV000093727 | MassIVE
ProteomicsLarge scale, quantitative top-down proteomic analysis of human frontal gyrus brain tissue samples in the context of Alzheimer's disease
15-35 mg brain tissue plugs derived from dorsal lateral prefrontal cortex (DLPFC) were homogenized on ice with a pellet pestle homogenizer in a 1.5 mL LoBind Eppendorf tube after addition of 8 uL hexafluoroisopropanol (HFIP) / mg tissue. Once tissue was fully disrupted, an equivolume amount of homog...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-12-26 | MSV000093728 | MassIVE
MetabolomicsMetabolomic profiling of Fraxinus excelsior genotypes tolerant or susceptible to ash dieback disease reveals changes in iridoid glycosides
European common ash, Fraxinus excelsior L., is currently threatened by Ash dieback (ADB) caused by the fungus, Hymenoscyphus fraxineus. To detect and identify metabolites that may be products of pathways important in contributing to resistance against H. fraxineus we performed untargeted metabolomic...
2016-11-09 | MTBLS372 | MetaboLights
UnknownJunD, not c-Jun, is the AP-1 transcription factor required for Ras-induced lung cancer.
Not available
S-EPMC8410048 | biostudies-literature
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