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A progressive loss of protein homeostasis is characteristic of aging and a driver of neurodegeneration. To investigate this process quantitatively, we characterized proteome dynamics during brain aging in the short-lived vertebrate Nothobranchius furzeri combining transcriptomics and proteomics. We ...
ORGANISM(S): Nothobranchius furzeri 
2020-06-22 | PXD016459 | Pride
A progressive loss of protein homeostasis is characteristic of aging and a driver of neurodegeneration. To investigate this process quantitatively, we characterized proteome dynamics during brain aging in the short-lived vertebrate Nothobranchius furzeri combining transcriptomics and proteomics. We ...
ORGANISM(S): Struthio camelus (Ostrich) Pisum sativum (Garden pea) Mus musculus (Mouse) Olea europaea (Common olive) Nothobranchius furzeri Vigna mungo (Rice bean) (Black gram) Pongo pygmaeus (Bornean orangutan) Sus scrofa domesticus (domestic pig) Merluccius bilinearis (Silver hake) Rattus rattus (Black rat) Mesocricetus auratus (Golden hamster) Zea mays (Maize) Rattus norvegicus (Rat) Taeniopygia guttata (Zebra finch) (Poephila guttata) Pan troglodytes (Chimpanzee) Trypanosoma brucei Pinus radiata (Monterey pine) Nicotiana tabacum (Common tobacco) Oryza sativa (Rice) Vitis vinifera (Grape) Ricinus communis Solanum tuberosum (Potato) Triticum aestivum (Wheat) Saccharomyces cerevisiae (Baker's yeast) Yarrowia lipolytica (Candida lipolytica) Xenopus laevis (African clawed frog) Staphylococcus aureus 
2020-06-22 | PXD016587 | Pride
Visual cortical circuits show profound plasticity during early life and are later stabilized by molecular "brakes" limiting excessive circuit rewiring beyond a critical period. How the appearance of these factors is coordinated during the transition from development to adulthood remains unknown. We ...
ORGANISM(S): Mus musculus (Mouse) 
2020-11-04 | PXD016430 | Pride
Visual cortical circuits show profound plasticity during early life and are later stabilized by molecular "brakes" limiting excessive circuit rewiring beyond a critical period. How the appearance of these factors is coordinated during the transition from development to adulthood remains unknown. We ...
ORGANISM(S): Mus musculus (Mouse) 
2020-11-04 | PXD016358 | Pride
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