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TranscriptomicsMycobacterial cells have dual nickel-cobalt sensors: sequence-relationships and metal-sites of metal-responsive repressors are not congruent.
A novel ArsR-SmtB family transcriptional repressor, KmtR, has been characterised from mycobacteria. Mutants of M. tuberculosis lacking kmtR show elevated expression of Rv2025c encoding a deduced CDF-family metal-exporter. KmtR-dependent repression of the cdf and kmtR operator-promoters was alleviate...
ORGANISM(S): Mycobacterium tuberculosis 
2007-09-17 | E-BUGS-49 | biostudies-arrayexpress
UnknownDynamics of the human skin mediator lipidome in response to dietary ω-3 fatty acid supplementation.
Not available
S-EPMC6902719 | biostudies-literature
GenomicsTransient expression of Bcl6 is sufficient for oncogenic function and induction of mature B-cell lymphoma
Reduced representation bisulfite sequencing (RRBS) of hematopoeitic stem/progenitor cells and mature B-cells from wild-type mice and mice transiently expressing Bcl6 under control of the Sca1 promoter. CBAxC57BL/6J mice were engineered to transiently express a Bcl6 cDNA in hematopoeitic stem/progeni...
ORGANISM(S): Mus musculus 
2014-03-28 | E-GEOD-56310 | biostudies-arrayexpress
GenomicsHigh definition profiling of mammalian DNA methylation by array capture and single molecule bisulfite sequencing
DNA methylation stabilizes developmentally programmed gene expression states. Aberrant methylation is associated with disease progression and is a common feature of cancer genomes. Presently, few methods enable quantitative, large-scale, single-base resolution mapping of DNA methylation states in d...
ORGANISM(S): Homo sapiens 
2009-07-08 | E-GEOD-17001 | biostudies-arrayexpress
UnknownEvaluation of 16S rRNA qPCR for detection of Mycobacterium leprae DNA in nasal secretion and skin biopsy samples from multibacillary and paucibacillary leprosy cases.
Not available
S-EPMC6056823 | biostudies-literature
TranscriptomicsTranscriptional profiling of a novel mutant resistant to imidacloprid and DDT
Deep-sequencing analysis of mRNA expression differences between imidacloprid and DDT resistant mutant line and iso31 (w1118) susceptible line have been obtained. A total of 357 transcripts were found to be differently expressed, with 150 upregulated and 207 downregulated genes in the resistant line....
ORGANISM(S): Drosophila melanogaster 
2012-06-27 | E-GEOD-28560 | biostudies-arrayexpress
UnknownSleep-Related Problems and the Effects of Anxiety Treatment in Children and Adolescents.
Not available
S-EPMC4833728 | biostudies-literature
UnknownTargeted inhibition of eIF4A suppresses B-cell receptor-induced translation and expression of MYC and MCL1 in chronic lymphocytic leukemia cells.
Not available
S-EPMC8429177 | biostudies-literature
UnknownA novel iris transillumination grading scale allowing flexible assessment with quantitative image analysis and visual matching.
Not available
S-EPMC6009845 | biostudies-literature
UnknownSingle-cell transcriptomics reveals a distinct developmental state of KMT2A-rearranged infant B-cell acute lymphoblastic leukemia.
Not available
S-EPMC9018413 | biostudies-literature
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