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UnknownHERMIONE: a randomized Phase 2 trial of MM-302 plus trastuzumab versus chemotherapy of physician's choice plus trastuzumab in patients with previously treated, anthracycline-naive, HER2-positive, locally advanced/metastatic breast cancer.
Not available
S-EPMC4893300 | biostudies-literature
TranscriptomicsMycobacterium tuberculosis efpA CRISPRi knock-down transcriptional profile - induced efpA knock-down strain vs non-induced condition
In Mycobacterium tuberculosis, the efflux pump, EfpA, plays an essential but uncharacterised role in its physiology and antibiotic tolerance. In this study, an ATc-inducible CRISPR interference (CRISPRi) system was introduced into M. tuberculosis to knock-down the expression of efpA and determine an...
ORGANISM(S): Mycobacterium tuberculosis 
2024-06-19 | E-MTAB-13755 | biostudies-arrayexpress
TranscriptomicsQuantification of global transcription patterns in prokaryotes using spotted microarrays
We describe an analysis, applicable to any spotted microarray dataset produced using genomic DNA as a reference, which quantifies prokaryotic levels of mRNA on a genome-wide scale. Applying this to Mycobacterium tuberculosis, we validate the technique, show a correlation between level of expression...
ORGANISM(S): Mycobacterium bovis 
2008-09-30 | E-BUGS-60 | biostudies-arrayexpress
UnknownHealth-adjusted life expectancy in HIV-positive and HIV-negative men and women in British Columbia, Canada: a population-based observational cohort study.
Not available
S-EPMC5761654 | biostudies-literature
UnknownTropospheric ozone assessment report: Global ozone metrics for climate change, human health, and crop/ecosystem research.
Not available
S-EPMC6192432 | biostudies-literature
UnknownAnalysis of the measurements used as potency tests for the 31 US FDA-approved cell therapy products.
Not available
S-EPMC11877884 | biostudies-literature
UnknownRecent declines in salmon body size impact ecosystems and fisheries.
Not available
S-EPMC7438488 | biostudies-literature
UnknownTIA1 Mutations in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Promote Phase Separation and Alter Stress Granule Dynamics.
Not available
S-EPMC5576574 | biostudies-literature
UnknownlncRNA Epigenetic Landscape Analysis Identifies EPIC1 as an Oncogenic lncRNA that Interacts with MYC and Promotes Cell-Cycle Progression in Cancer.
Not available
S-EPMC6143179 | biostudies-literature
UnknownCharacterizing Heterogeneity in Neuroimaging, Cognition, Clinical Symptoms, and Genetics Among Patients With Late-Life Depression.
Not available
S-EPMC8908227 | biostudies-literature
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