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TranscriptomicsTranscriptional profiling of laser-captured spinal motor neurons in the AR100 mouse model of spinal and bulbar muscular atrophy across disease stages
Laser-captured motor neurons (LCM-MN) from spinal cord sections of AR100 SBMA mice and AR20 wild-type controls were isolated at presymptomatic (3 months), symptomatic (12 months), and late-stage (18 months) time points. RNA-seq profiling was performed using Illumina HiSeq paired-end sequencing to in...
ORGANISM(S): Mus musculus 
2026-08-01 | E-MTAB-15768 | biostudies-arrayexpress
UnknownLongitudinal Plasma Metabolomics Profile in Pregnancy-A Study in an Ethnically Diverse U.S. Pregnancy Cohort.
Not available
S-EPMC8471130 | biostudies-literature
GenomicsDNA-seq of mitochondrial DNA from mouse heart that is both heart SOD2 knockout and deficient for mitochondrial DNA repair
To study whether increase in mitochondrial oxidative stress (SOD2 removal) and decrease in mitochondrial DNA repair (Ogg1 dMTS) results into increase in mitochondrial DNA mutation load. Oxidative stress has been suggested to induce mutations in mtDNA. To verify this, we extracted and sequenced (Illu...
ORGANISM(S): Mus musculus 
2018-07-13 | E-MTAB-6533 | biostudies-arrayexpress
UnknownNitrogen fertilization reduces the standing biomass, abundance, and size of Cenococcum sclerotia: a ubiquitous but rarely quantified ectomycorrhizal soil carbon pool.
Not available
S-EPMC12824604 | biostudies-literature
UnknownBlood and hair manganese concentrations in pregnant women from the infants' environmental health study (ISA) in Costa Rica.
Not available
S-EPMC3983325 | biostudies-literature
UnknownDeveloping a hetero-alkali-metal chemistry of 2,2,6,6-tetramethylpiperidide (TMP): stoichiometric and structural diversity within a series of lithium/sodium, lithium/potassium and sodium/potassium TMP compounds.
Not available
S-EPMC3761191 | biostudies-literature
UnknownDisruption of O-Linked N-Acetylglucosamine Signaling in Placenta Induces Insulin Sensitivity in Female Offspring.
Not available
S-EPMC8267851 | biostudies-literature
TranscriptomicsTranscriptional profiling of iPSC derived motor neurons from spinal and bulbar muscular atrophy patients at key stages motor neurogenesis
Characterise the molecular pathogenesis of androgen receptor spinal and bulbar muscular atrop (SBMA) causing repeat expansion mutations in human motor neurons generated from patient-specific spinal cord motor neurons from induced pluripotent stem cells and performed time-resolved analysis of transcr...
ORGANISM(S): Homo sapiens 
2026-08-01 | E-MTAB-15765 | biostudies-arrayexpress
TranscriptomicsHuman keratinocytes have a response to injury that upregulates CCL20 and other genes linking innate and adaptive immunity
In the early stages of wound healing, keratinocytes become “activated” and release inflammatory molecules such as interleukin-1 and interleukin-8 that are linked to innate immune responses and neutrophil recruitment. It is unclear, however, whether keratinocytes release molecules linked to adaptive ...
ORGANISM(S): Homo sapiens 
2011-09-19 | E-GEOD-30355 | biostudies-arrayexpress
UnknownFemale genital cutting (FGC) type: proposing a multifaceted, interactive method for FGC self-assessment.
Not available
S-EPMC10627780 | biostudies-literature
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